Incidence and Predicting Factors of Vaginal Stenosis in Gynecological Cancer Patients Receiving Radiotherapy and Brachytherapy


  • Pratsani Srikan Boromarajonni College of Nursing Phayao, Faculty of Nursing, Prabormrajanko Institute, Thailand
  • Kanyarat Wannavong Lampang Cancer Hospital, Lampang, Thailand
  • Kanchana Daoprasert Lampang Cancer Hospital, Lampang, Thailand
  • Yupin Chainam Lampang Cancer Hospital, Lampang, Thailand
  • Waraporn Chaitan Lampang Cancer Hospital, Lampang, Thailand


vaginal stenosis, radiation therapy, brachytherapy, gynecological cancer


Background: Vaginal stenosis is a common effect in gynecological cancer patients who have undergone radiation or brachytherapy. Purposes: This study aimed to explore the incidence and predictive factors of vaginal stenosis in gynecological cancer patients. Research Methodology: It was a retrospective study. Seven hundreds and nineteen medical records of gynecological cancer patients receiving radiotherapy and brachytherapy in Lampang Cancer Hospital from January 1, 2013 to December 31, 2017 were reviewed. The history of follow up for at least 3 months after the treatments was studied. The factors assessed included patient’s age, marital status, underlying disease, type of cancer, total amount of radiation, radiation dose, radiation fraction, total amount of brachytherapy, brachytherapy dose, brachytherapy fraction, and chemotherapy. Results: 60% of the sample aged were between 41 and 60 years (Range = 23 - 90 years, Mean = 56.11 years, SD. = 11.60 years), and 94.20% had been married. Also, 86.40% were cervical cancer patients. The incidence of vaginal stenosis was 23%, with Grade 2 vaginal stenosis occurred 1-12 months after treatment ended (61.03%). The total amount of radiation (Beta = .157) and age (Beta = .123) were statistically significant predictors of vaginal stenosis. Conclusion: The total amount of radiation and age play a crucial roles in contributing vaginal stenosis. Implications: Therefore, patients who have high-radiation dose and are over 50 years of age should be regularly monitored for the occurrence of vaginal stenosis and should be advised to use a vaginal dilatator.


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How to Cite

Srikan ป, Wannavong ก, Daoprasert ก, Chainam ย, Chaitan ว. Incidence and Predicting Factors of Vaginal Stenosis in Gynecological Cancer Patients Receiving Radiotherapy and Brachytherapy. JHNR [Internet]. 2021 Apr. 9 [cited 2022 Jun. 26];37(1):281-93. Available from:



Research articles