Understanding towards Medications and Medication Adherence among HIV-Infection /AIDs Patients: Case study in a Hospital in Sakon Nakhon
Main Article Content
Abstract
Objective: To examine understanding on medications and medication adherence among HIV/AIDS patients, and to study the relationship between these two variables. Method: This research was a cross-sectional study in 280 subjects selected by convenience sampling. Medication adherence was measured by pill counting. The Thai Medication Understanding Questionnaire was used to assess understanding on medications. Results: Most of the participants had good understanding on medication (having the score equal or greater than 5) and medication adherence was at a good level (97.75% of adherence). The medication understanding and medication adherence were positively and significantly correlated (P<0.05). The study also revealed the relationship between drug understanding and personal factors including occupations, duration of drugs taking, experiences of side effects from antiviral drugs, CD4 cell level, and viral load (P<0.05). Moreover, the study also found the relation between medication adherence and health benefit schemes (P<0.05). Conclusions: The study revealed a correlation between medication understanding and medication adherence and factors associated with medication understanding and medication adherence. The results of the study could be used to develop a patient care model to help them realize the importance of medication taking to suppress the virus load, which is an important target of antiretroviral therapy.
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
References
World Health Organization. Global health sector strategy on HIV 2016–2021 [online]. 2018 [cited Nov 10, 2018]. Available from: www.who.int/hiv/stra tegy2016-2021/ghss-hiv/en/
UNAIDs. UNAIDS data 2017 [online]. 2017 [cited Nov 12, 2018]. Available from: www.unaids.org/site s/default/files/media_asset/2017_data-book_en.pdf
UNAIDS. UNAIDS data 2018 [online]. 2018 [cited Nov 18, 2018]. Available from: www.unaids.org/site s/default/files/media_asset/unaids-data-2018_en.pdf
World Health Organization. Section I setting the scene [online]. 2003 [cited Dec 7, 2018]. Available from: www.who.int/chp/knowledge/publications/adhe rence_Section1.pdf
Long JM, Kee CC, Graham M V, Saethang TB, Dames FD. Medication compliance and the older hemodialysis patient. ANNA J 1998; 25: 43–9.
Bangsberg DR. Less than 95% adherence to non- nucleoside reverse-transcriptase inhibitor therapy can lead to viral suppression. Clin Infect Dis. 2006; 43: 939–41.
Mannheimer S, Friedland G, Matts J, Child C, Chesney M. The consistency of adherence to anti- retroviral therapy predicts biologic outcomes for human immunodeficiency virus–infected persons in clinical trials. Clin Infect Dis. 2002; 34: 1115–21.
Mhothong P, Thongkot W, Aungpanyasattawong S. Determining the sample size by the Yamane’s formula. DPU Res. :1–12.
Marvanova M, Roumie CL, Eden SK, Cawthon C, Schnipper JL, Kripalani S. Health literacy and medication understanding among hospitalized adults. J Hosp Med. 2011; 6: 488–93.
Srirach C, Boonshuyar C, Pacheun O. View of health behaviors and adherence to antiretroviral drug among people living with human immunedefi ciency virus. J Nursing Siam Univ 2018; 19: 39–55.
Hfocus. AIDs: epidemics with no vaccines [online]. 2020 [cited May 21, 2021]. Available from: /www. hfocus.org/content/2020/05/19271
March K, Mak M, Louie SG. Effects of pharma- cists’ interventions on patient outcomes in an HIV primary care clinic. Am J Heal Pharm. 2007; 64: 2574–8.
Saberi P, Dong BJ, Johnson MO, Greenblatt RM, Cocohoba JM. The impact of HIV clinical pharma- cists on HIV treatment outcomes: a systematic review. Patient Prefer Adherence 2012; 6: 297-322.
Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133: 21-30.
Hu Y. The Study of Type 2 Diabetes in China: Patient Medication Understanding and Medication Adherence; Physician Prescribing Patterns and Attitudes toward Traditional Chinese Medicine. J Med Assoc Thai 2020; 103(10): 1004-10.
Kripalani S, Laura E, Chiu Y, Robertson R, Kolm P, Terry A. Predictors of medication self-manage ment skill in a low-literacy population setting and population. J Gen Intern Med. 2006; 21: 852-6. doi: 10.1111/j.1525-1497.2006.00536.x.