Development of the Medication Adherence Scale for Thais (MAST)
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Abstract
Objectives: To develop the Medication Adherence Scale for Thais (MAST) and to find the cut off score to determine the level of medication adherence (MA). Method: The measure was tested for content validity by the review of 3 experts. The measure was pilot-tested in 30 hypertensive patients. It was further tested in 250 patients with hypertension at Pattani Hospital. The study administered the MAST, the SF-36, and the Marlowe-Crowne Social Desirability Scale (MCSD) to the subjects at month 0 and 6 at the end of the research. The researchers also collected the data on blood pressure and counted the remaining pills at month 0, 2, 4 and 6. Cut-off score was determined using analysis of receiver operator characteristics (ROC) curve. Result: Cronbach's alpha coefficients of the MAST in month 0 and month 6 were 0.87 and 0.86, respectively. The test-retest reliability was satisfactory (r=0.90). The MAST was correlated with MA assessed by pill counts (r=0.56-0.64; P<0.001) and SF-36 (r=0.43-0.44, P<0.001), but showed no correlation with the MCSD (r=-0.086, P=0.175). Using blood pressure control at month 6 as the gold standard for MA, area under the ROC was 0.73. Appropriate cut-off score was 34 with sensitivity of 71.30%, specificity of 69.10%, positive predictive value of 61.02% and negative predictive value of 78.03%. Conclusion: The MAST as a measure of MA shows good reliability and validity. Furthermore, it exhibited high sensitivity, specificity and predictive value suitable for assessing MA in hypertensive patients.
Article Details
ผลการวิจัยและความคิดเห็นที่ปรากฏในบทความถือเป็นความคิดเห็นและอยู่ในความรับผิดชอบของผู้นิพนธ์ มิใช่ความเห็นหรือความรับผิดชอบของกองบรรณาธิการ หรือคณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ ทั้งนี้ไม่รวมความผิดพลาดอันเกิดจากการพิมพ์ บทความที่ได้รับการเผยแพร่โดยวารสารเภสัชกรรมไทยถือเป็นสิทธิ์ของวารสารฯ
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