Prevalence of Abnormal Cervical Cancer Screening Results Among Pregnant Women at Lampang Hospital
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Abstract
Background: Cervical cancer is the fourth most common cancer among Thai women. Lampang Hospital has implemented a policy of cervical cancer screening using liquid-based cytology (LBC) for all pregnant women attending antenatal care. However, data on the prevalence of abnormal screening results in this population remain limited.
Objective: To determine the prevalence of abnormal cervical cancer screening results in pregnant women and the prevalence of cervical intraepithelial neoplasia grade 2 or higher (CIN2+) among those with abnormal results who underwent postpartum cervical biopsy.
Materials and Methods: This retrospective study included pregnant women who attended antenatal care and underwent cervical cancer screening using LBC at Lampang Hospital between June 1, 2020, and March 31, 2023. Descriptive statistics were used to analyze the data, and comparisons were made between women with normal and abnormal screening results.
Results: A total of 1,163 pregnant women were screened. Abnormal results were found in 71 cases (6.1%), including: atypical squamous cells of undetermined significance (ASCUS) in 45 cases (3.8%), low-grade squamous intraepithelial lesion (LSIL) in 20 cases (1.7%), atypical squamous cells cannot exclude HSIL (ASC-H) in 2 cases (0.2%), highgrade squamous intraepithelial lesion (HSIL) in 3 cases (0.3%), and 1 case of cervical cancer detected through visible lesion biopsy (0.1%). A history of prior childbirth was observed in 57.2% of women with normal screening results, compared to 70.4% in the abnormal screening group (p = 0.034). Among women with abnormal results, 26 (37.1%) underwent postpartum colposcopy and cervical biopsy, revealing 8 cases of CIN1 and 2 cases of CIN2+. Including the one case of cervical cancer detected during pregnancy, there were a total of 3 CIN2+ cases among 27 women with abnormal screening results who underwent confirmatory biopsy, yielding a CIN2+ prevalence of 11.1%.
Conclusion: Cervical cancer screening during pregnancy detected abnormal results in 6.1% of cases. Among those with abnormal screening who underwent postpartum biopsy, 11.1% had high-grade precancerous lesions (CIN2+).
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บทความที่ส่งมาลงพิมพ์ต้องไม่เคยพิมพ์หรือกำลังได้รับการพิจารณาตีพิมพ์ในวารสารอื่น เนื้อหาในบทความต้องเป็นผลงานของผู้นิพนธ์เอง ไม่ได้ลอกเลียนหรือตัดทอนจากบทความอื่น โดยไม่ได้รับอนุญาตหรือไม่ได้อ้างอิงอย่างเหมาะสม การแก้ไขหรือให้ข้อมูลเพิ่มเติมแก่กองบรรณาธิการ จะต้องเสร็จสิ้นเป็นที่เรียบร้อยก่อนจะได้รับพิจารณาตีพิมพ์ และบทความที่ตีพิมพ์แล้วเป็นสมบัติ ของลำปางเวชสาร
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