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Background: In Thailand, the prevalence of high-grade squamous intraepithelial lesions (HSIL) and invasive cervical cancer among patients with atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H). Cervical cytology varies widely from 26.3 to 69% and 4.5 to 20%,respectively. Information regarding the prevalence and associated factors in each particular area is thus important for planning appropriate management.
Objective: To determine the prevalence and risks of encountering HSIL and invasive cervical cancer among patients with ASC-H cervical cytology who underwent colposcopy in Lampang Hospital. Treatment outcomes were also assessed by the type of intervention received.
Material and method: From January 2009 to December 2018, 184 patients were included in this retrospective cohort study. Abstract data consisted of baseline clinical characteristics, most significant histologic results, types of treatment received, and the treatment outcomes during follow-up. Associated factors were assessed by using univariate regression analysis.
Results: Prevalence of HSIL and invasive cervical cancer were 35.3% and 6%, respectively. Only menopausal status was noted to be related to the risk of having underlying significant cervical lesion. Premenopausal patients were 2.4- times (95% CI 1.21-4.77) more likely to encounter with HSIL and invasive cancer compared to those in the postmenopausal group. Prevalence of high-grade squamous cervical smear or cancer abnormality during follow-up among 3 groups of patients who underwent follow-up alone, loop electrosurgical excision procedure, and hysterectomy were 2.6%, 2.6%, and 7.2% respectively.
Conclusion: The significant pathology results among patients with ASC-H smear in Lampang Hospital was 41.3 % and the associated factor was meno-pausal
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บทความที่ส่งมาลงพิมพ์ต้องไม่เคยพิมพ์หรือกำลังได้รับการพิจารณาตีพิมพ์ในวารสารอื่น เนื้อหาในบทความต้องเป็นผลงานของผู้นิพนธ์เอง ไม่ได้ลอกเลียนหรือตัดทอนจากบทความอื่น โดยไม่ได้รับอนุญาตหรือไม่ได้อ้างอิงอย่างเหมาะสม การแก้ไขหรือให้ข้อมูลเพิ่มเติมแก่กองบรรณาธิการ จะต้องเสร็จสิ้นเป็นที่เรียบร้อยก่อนจะได้รับพิจารณาตีพิมพ์ และบทความที่ตีพิมพ์แล้วเป็นสมบัติ ของลำปางเวชสาร
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