Factors that influcence the major bleeding in various patients on chronic warfarin therapy
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Abstract
Warfarin has been used extensively as an anticoagulant for a variety of disease. The factors that influence the major bleeding
in various patients on chronic warfarin therapy were studied. A retrospective cohort study was conducted on patients who were
being seen in outpatient clinics. The record of 382 patients were reviewed. It has been founded that 54 patients had major bleeding.
Factors that influcnce the major bleeding were history of previous bleeding for 11 cases (IRR = 4.06% ; 95% Cl, 1.93 - 8.57) p <
0.001 and aspirin for 5 cases (IRR = 2.635 ; 95% Cl = 1.03 - 6.69) p < 0.042. In conclusion, the history of previous bleeding and
aspirin were factors that influnce the major bleeding, physician ahould monitors these factors closely in patients who had been
on wafarin therapy to prevent risk of major bleeding.
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บทความที่ส่งมาลงพิมพ์ต้องไม่เคยพิมพ์หรือกำลังได้รับการพิจารณาตีพิมพ์ในวารสารอื่น เนื้อหาในบทความต้องเป็นผลงานของผู้นิพนธ์เอง ไม่ได้ลอกเลียนหรือตัดทอนจากบทความอื่น โดยไม่ได้รับอนุญาตหรือไม่ได้อ้างอิงอย่างเหมาะสม การแก้ไขหรือให้ข้อมูลเพิ่มเติมแก่กองบรรณาธิการ จะต้องเสร็จสิ้นเป็นที่เรียบร้อยก่อนจะได้รับพิจารณาตีพิมพ์ และบทความที่ตีพิมพ์แล้วเป็นสมบัติ ของลำปางเวชสาร
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