Factors Associated with Uncontrolled Hypertension in Patients with Type 2 Diabetes in Lampang Hospital
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Abstract
Backgroud : Hypertension control is one of the most important goal for treating type 2 diabetes. The blood pressure (BP) normalization rate of diabetic patients in Lampang Hospital declined every year.
Objective : To investigate the factors associated with hypertension control in the patients with
type 2 diabetes in Lampang Hospital.
Material and method : A cross-sectional analytical study of outpatients with type 2 diabetes and hypertension was conducted in Lampang Hospital between 15th December 2011 and 15th
February 2012. The patients were divided into controlled group (BP<130/80 mmHg) and
uncontrolled group (BP≥130/80 mmHg). Clinical and laboratory data were analyzed with t-test,
Chi-square test and Fisher’s exact test. Factors associated with uncontrolled BP were analyzed
by logistic regression.
Results : Among 260 hypertensive patients with type 2 diabetes, 60.4% were female. The mean age was 59.9±10.7 years and mean BP was 138.9±19.5 / 73.9±12.9 mmHg. The mean fasting blood sugar and serum creatinine were 146.5±49.6 mg/dl and 1.0±0.4 mg/dl respectively. The uncontrolled group (147 patients, 56.5%) had significantly higher serum triglyceride (p=0.005) and albuminuria (p=0.024). Patients with uncontrolled BP received more items of antihypertensive drugs (2.2±1.2 vs 1.9±1.0, p=0.024). The significant factors associated
with uncontrolled hypertension were presence of macroalbuminuria (OR=2.74, 95%CI 1.09-6.89, p=0.032) and serum triglyceride ≥150 mg/dl (OR=1.84, 95%CI 1.10-3.06, p=0.019).
Conclusion : Macroalbuminuria and hypertriglyceridemia were risk factors of uncontrolled
hypertension in type 2 diabetic patients in Lampang Hospital.
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บทความที่ส่งมาลงพิมพ์ต้องไม่เคยพิมพ์หรือกำลังได้รับการพิจารณาตีพิมพ์ในวารสารอื่น เนื้อหาในบทความต้องเป็นผลงานของผู้นิพนธ์เอง ไม่ได้ลอกเลียนหรือตัดทอนจากบทความอื่น โดยไม่ได้รับอนุญาตหรือไม่ได้อ้างอิงอย่างเหมาะสม การแก้ไขหรือให้ข้อมูลเพิ่มเติมแก่กองบรรณาธิการ จะต้องเสร็จสิ้นเป็นที่เรียบร้อยก่อนจะได้รับพิจารณาตีพิมพ์ และบทความที่ตีพิมพ์แล้วเป็นสมบัติ ของลำปางเวชสาร
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