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Type 2 diabetes mellitus patients (T2DM) are at risk for several complications including cerebrovascular disease, diabetic retinopathy, amputation, and diabetic nephropathy. The goals of diabetes management are optimal glycemic control and reduce risk factors through medication and behavior to reduce risk factors. Health literacy (HL) in T2DM is the degree which individual can obtain the health information, communicate health information, understand the information regarding diabetes, and understand the process of self-care in order to make health decisions. Therefore, T2DM who have optimal HL will be able to manage their health. This article aims to describe definition and the principle for treatment of T2DM, definition of HL, the significance of HL in chronic disease, the association between HL and health outcome in T2DM, and the improvement of intervention to enhance effectiveness of HL in T2DM that may be contributed to achieve desirable health outcome in T2DM.
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