PREVALENCE AND ASSOCIATED FACTORS OF METABOLIC SYNDROME AMONG PSYCHIATRIC INPATIENTS AT SOMDET CHAOPRAYA INSTITUTE OF PSYCHIATRY
Keywords:
metabolic syndrome, psychiatric patient, inpatientAbstract
Objectives: To assess the prevalence and associated factors of metabolic syndrome among psychiatric inpatients at Somdet Chaopraya Institute of Psychiatry.
Material and Methods: This was a cross-sectional study of patients admitted at Somdet Chaopraya Institute of Psychiatry between May and August 2021. The research tools used were 1) metabolic syndrome was determined using the International Diabetes Federation (IDF) criteria 2) general data record form 3) clinical data and 4) medicine received. The statistics used were frequency, percentage, mean and standard deviation. In addition, associated factors were computed using chi-square test and logistic regression.
Results: 315 patients were included, of whom 193 were male and 122 were female. The prevalence of metabolic syndrome was 22.2% (n = 70). The associated factors of metabolic syndrome among this group of patients were age between 40 - 60 years (OR = 2.03, 95%CI = 1.17, 3.51), family history of hypertension (OR = 2.20, 95%CI = 1.07, 4.50), duration of illness more than 10 years (OR = 2.10, 95%CI = 1.16, 3.82) and admission rate more than 2 times per year (OR = 1.90, 95%CI = 1.01, 3.61). In multiple logistic regression analyses, we found that admission rate more than 2 times per year was more risk factor of metabolic syndrome compared to admission rate 0 - 1 times per year with adjusted odds ratios of 2.48 (95%CI: 1.23, 5.00).
Conclusion: The prevalence of metabolic syndrome was found to be common in psychiatric patients. Associated factors that should receive more attention when performing history taking were age, family history of hypertension, duration of illness more than 10 years and admission rate more than 2 times per year.
References
Hirode G, Wong RJ. Trends in the prevalence of metabolic syndrome in the United States 2011-2016. JAMA 2020; 323: 2526-28.
วิชัย เอกพลากร. ภาวะสุขภาพ ใน: วิชัย เอกพลากร, บรรณาธิการ. การสำรวจสุขภาพประชาชนไทยโดยการตรวจร่างกาย ครั้งที่ 5 พ.ศ.2557. กรุงเทพฯ: สำนักพิมพ์อักษรกราฟฟิคแอนด์ดีไซน์; 2559: 170.
Sood PG, Lally J, Smith S, Atakan Z, Ismail K, Greenwood KE, et al. Cardiovascular risk factors and metabolic syndrome in people with established psychotic illnesses: baseline data from the Impact randomized controlled trial. Psychol Med 2015; 45: 2619-29.
Osborn D, Levy G, Nazareth I, Petersen I, Islam A, Michael B. Relative risk of cardiovascular and cancer mortality in people with severe mental illness from the united kingdom's general practice research database. Arch Gen Psychiatry 2007; 64: 242-9.
Pillinger T, McCutcheon R, Vano L, Mizuno Y, Arumuham A, Hindley G, et al. Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis. Lancet Psychiatry 2020; 7: 64-77.
จินตนา มงคลพิทักษ์สุข. ภาวะเมตาบอลิกซินโดรมในผู้จิตเภท. วารสารสถาบันจิตเวชศาสตร์สมเด็จเจ้าพระยา 2551; 2: 36-44.
Moreira FP, Jansen K, de A Cardoso T, Mondin T, Magalhaes P, Kapczinski F, et al. Metabolic syndrome and psychiatric disorders: a population-based study. Braz J Psychiatry 2019; 41: 38-43.
ICD-10 Version 2010 Chapter V Mental and behavioural disorders (F00-F99) [online]. Available from: https://icd.who.int/ browse10/2010/en#/V [2021 Nov 15].
Bressington DT, Mui J, Cheung EFC, Petch J, Clark AB, Gray R. The prevalence of metabolic syndrome amongst patients with severe mental illness in the community in Hong Kong - a cross sectional study. BMC Psychiatry 2013; 13: 87
Santini I, Stratta P, D’Onofrio S, DeLauretis I, Santarelli V, Pacitti F, Rossi A. The metabolic syndrome in an Italian psychiatric sample: a retrospective chart review of inpatients treated with antipsychotics. Riv Psichiatr 2016; 51(1): 37-42
Silarova B, Giltay EJ, VanReedt DA, VanRossum E, Hoencamp E, Penninx B, et al. Metabolic syndrome in patients with bipolar disorder: Comparison with major depressive disorder and non-psychiatric controls. J Psychosom Res 2015; 78: 391-8.
Al-Qahtani DA, Imtiaz ML. Prevalence of metabolic syndrome in Saudi adult soldiers. Saudi Med J 2005; 26: 1360-6.
Ranasinghe P, Cooray DN, Jayawardena R, Katulanda P. The influence of family history of Hypertension on disease prevalence and associated metabolic risk factors among Sri Lankan adults. BMC Public Health 2015; 15: 576.
Alosaimi FD, Abalhassan M, Alhaddad B, Alzain N, Fallata E, Alhabbad A, Alassiry MZ. Prevalence of metabolic syndrome and its components among patients with various psychiatric diagnoses and treatments: A cross-sectional study. Gen Hosp Psychiatry 2017; 45: 62-9.
Khanna N, Sharma RS, Sidhu RS. A study of the basic and derived anthropometric indices among the healthy adults (20-30 years of age) of amritsar city (punjab) having family history of hypertension. Int J Biol Med Res 2011; 2(3): 743-6.
Tony C, Denis P, David S, Homa K, Gary R. Characterizing coronary heart disease risk in chronic schizophrenia: high prevalence of the metabolic syndrome. Can J Psychiatry 2004; 49(11): 753-60.
Godin O, Leboyer M, Schürhoff F, Llorca PM, Boyer L, Andre M, et al. Metabolic syndrome and illness severity predict relapse at 1-year follow-up in schizophrenia. J Clin Psychiatry 2018; 79(6): e1-e9.
Centorrino F, Masters GA, Talamo A, Baldessarini RJ, Öngür D. Metabolic syndrome in psychiatrically hospitalized patients treated with antipsychotics and other psychotropics. Hum Psychopharmacol 2018; 27(5): 521-6.
Ko YK, Soh MA, Kang SH, Lee JI. The prevalence of metabolic syndrome in schizophrenic patients using antipsychotics. Clin Psychopharmacol Neurosci 2013; 11(2): 80-8.
Pillinger T, McCutcheon RA, Vano L, Mizuno Y, Arumuhan A, Hindley G, et al. Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis. Lancet Psychiatry 2020; 7(1): 64-77.
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