Factors Associated with Perceived Cognitive Function in Colorectal Cancer Patients Receiving Chemotherapy

Kruawan  Santhuankaew; Bualuang   Sumdaengrit; Apinya   Siripitayakunkit

Authors

Kruawan Santhuankaew Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Bualuang Sumdaengrit Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Apinya Siripitayakunkit Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

Keywords:

Colorectal cancer, Chemotherapy, Cognitive function

Abstract

This study aimed to examine the correlation between doses of chemotherapy, anxiety levels, depression levels and cognitive functions. This study used conceptual model of chemotherapy-related changes in cognitive function of Hess and Insel (2007). The research participants were 65 patients with colorectal cancer who received chemotherapy in Lampang province selected by accidental sampling of the specified qualifications. The instruments consisted of demographic data form, Hospital Anxiety and Depression Scale Questionnaire (Thai HADS) and Functional Assessments Cancer Therapy - Cognitive function (FACT-Cog Version 3) Questionnaire. The data were analyzed by descriptive statistics, Pearson's correlation statistics and Spearman’s Rank correlation coefficient.

The results that the mean scores of perceived cognitive impairments were slightly low ( $gif.latex?\fn_phv&space;\bar{X}$ = 98.85, SD = 10.34). Moreover, the correlation analysis revealed that anxiety, depression and chemotherapy dose were significantly negatively correlated with perceived cognitive function

(r = -.47, p <.01, r = -. 49, p <.01 and r = -.42, p <.05 respectively)

The results of this study provide basic information that helps nurses and team to be aware of cognitive function assessments and to make nursing plans to reduce the factors related to cognitive impairment in patients with colorectal cancer who received chemotherapy effectively.

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