วิตามินดีกับภาวะอ้วนลงพุงในประชากรไทย Vitamin D and Metabolic Syndrome in Thais

Abstract

Objective: To determine the association between vitamin D and metabolic syndrome among Thai population and to determine the association between vitamin D and risk factors of metabolic syndrome.

Material and methods: A cross-sectional analytical study comprised 400 subjects who came for an annual check-up aged 18 years or older. They were classified as having metabolic syndrome based on the modified National Cholesterol Educational Program Adult Treatment Panel III (NCEP-ATP III) criteria. Serum 25(OH)D levels were measured using chemiluminescence immunoassay. The association between serum 25(OH)D levels and the metabolic syndrome was examined using multiple logistic regression analysis.

Results: The prevalence of vitamin D deficiency (<20 ng/ml) was 41%. There was no association between serum 25(OH)D and the metabolic syndrome after adjusting for sex, age, residential area, duration of sun exposure, smoking and alcohol intake. Furthermore, there was no association between vitamin D and risk factors of metabolic syndrome.

Conclusions:  A high prevalence of vitamin D deficiency was noted in Thai population group. However, it was not associated with metabolic syndrome or risk factors of metabolic syndrome.