Fluoride and its hematological effects including occurrence of dental fluorosis among school children in Omkoi District, Chiang Mai: The association between water management and fluorosis and mechanism of fluoride on hematological disorders

Authors

  • ฉัตร์ภัทร์ คงปั้น ศูนย์อนามัยที่ 2 พิษณุโลก, 21 หมู่ 4 ตำบลมะขามสูง อำเภอเมือง จังหวัดพิษณุโลก 65000

Keywords:

Hematological effect, Anemia, Complete Blood Cell, Fluoride, Dental Fluorosis

Abstract

This research aimed to study dental fluorosis prevalence and hematological disorders between high-risk and low-risk. Some water management groups influence factors on dental fluorosis was also studied. It was found that dental fluorosis was significantly associated with serum fluoride according to the prevalence of dental fluorosis that has been increased from 29.9% in the low-risk areas to 44.5% in the high-risk areas.  The results showed that various amounts of fluoride can induce various hematological effects. There were a significantly different in White Blood Cell (WBC), Hematocrit (Hct), Mean cell volume (MCV), Mean cell hemoglobin concentration (MCHC) and Platelets (Plt) values of high risk and low-risk group. This outcome was similar in subjects that serum fluoride > 0.043 mg/L and serum fluoride ≤ 0.043 mg/L except for WBC value that was not different. While the comparison of CBC value in safe (≤ 0.7 mg/L) and unsafe (> 0.7 mg/L) water fluoride level group showed a significantly different in mean MCV, MCHC and Plt values. Generalized Least Square Model analysis revealed that if controlling the amount of fluoride not to exceed the standard and finding safe drinking water sources for the public, it will reduce the risk of dental fluorosis by 2.72 times and 3.94 times, respectively. An important measure to solve the fluoride problem is to promote the appropriate water consumption behavior of people for risk reduction of receiving fluoride by having choices about water sources and using water for correct consumption. Including the need to monitor the disorders or symptoms associated with fluoride exposure, both disorders of the blood and teeth.

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Published

2019-12-31

How to Cite

คงปั้น ฉ. (2019). Fluoride and its hematological effects including occurrence of dental fluorosis among school children in Omkoi District, Chiang Mai: The association between water management and fluorosis and mechanism of fluoride on hematological disorders. Journal of Medicine and Public Health, Ubon Ratchathani University, 2(3), 205–217. Retrieved from https://he01.tci-thaijo.org/index.php/jmpubu/article/view/219640

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Research Articles