Clinical manifestations of dementia with Lewy bodies

Authors

  • Papan Thaipisuttikul Faculty of Medicine Ramathibodi Hospital Mahidol University
  • Pitchayawadee Chittaropas Faculty of Medicine Ramathibodi Hospital Mahidol University
  • Sudawan Jullagate Faculty of Medicine Ramathibodi Hospital Mahidol University

Keywords:

dementia, Lewy bodies, psychological symptom

Abstract

               Objective To study clinical manifestations of neurocognitive disorder with Lewy bodies patients (NCDLB).

               Materials and methods This was a prospective study of patients at memory and psychiatric clinic, Ramathibodi hospital from March 2014 to February 2016. All questionnaires were in Thai  language including, Mini-Mental Status Examination (MMSE-Thai), Neuropsychiatric Inventory (NPI-Q), Common psychotic symptoms in Dementia with Lewy bodies questionnaire, Parkinson’s disease screening questionnaire and Mayo sleep questionnaire-modifi ed version.

               Results There were 24 patients who met the criteria diagnosis of NCDLB. Average age was 72. Average education was high school level. Eight were mild and 16 were major NCDLB. Majority of patients with mild NCDLB presented with behavioral and psychological symptoms (BPSD), while patients with major NCDLB presented with both memory complaints and BPSD proportionately. Common BPSD in mild NCDLB were irritable, anxiety, depression, apathy and Capgras delusion. Common BPSD in major NCDLB were delusion, irritable, hallucination and sleeping problem.

                Conclusion Patients with mild NCDLB presented with BPSD more than memory problems while patients with major NCDLB had proportionately BPSD and memory complaints. These symptoms were different from Alzheimer disease patients.

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Published

2017-01-31

How to Cite

1.
Thaipisuttikul P, Chittaropas P, Jullagate S. Clinical manifestations of dementia with Lewy bodies. J Ment Health Thai [internet]. 2017 Jan. 31 [cited 2025 Apr. 25];25(1):47-58. available from: https://he01.tci-thaijo.org/index.php/jmht/article/view/129671

Issue

Vol. 25 No. 1 (2017)

Section

Original article

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