Latent Tuberculosis Infection Rate and TB Incidence among Healthcare Workers in Tertiary Hospitals
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Abstract
Healthcare workers are the high-risk group for latent tuberculosis (TB) infection. Up to now the studies of the incidence of convertor in the second year, active TB rate and completion rate of latent TB prevention with 3HP regimen are still limited among healthcare workers.
This study was a cross-sectional study from October 2018 to March 2020. An IGRA QuantiFERON-TB Gold Plus (QF-Plus) were used to determine latent TB status. Results showed that the conversion rate in the second year with 35 of 536 persons (6.5%). Factors associated with latent TB infection are the number of beds in the hospital (less than or equal 500 beds and more than 500 beds) with statistically significant (p<0.05), Moreover, an area health correlated to with latent TB infection with statistically significant (p<0.05).
The completion rate of latent TB prevention with 3HP regimen among healthcare workers with 24 of 29 (82.8%). Five of 29 discontinued treatment due to adverse events, rash is the major cause. Among 536 healthcare workers whom IGRA positive, the active TB rate founded 4 persons (0.7%). In summary, Tuberculosis is the major problem in health system in Thailand. Healthcare workers should be annual screened for latent tuberculosis. Early TB preventive treatment for latent TB could be help developing tuberculosis and ending TB in the future.
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บทความที่พิมพ์ในวารสารสถาบันป้องกันควบคุมโรคเขตเมือง ถือว่าเป็นผลงานวิชาการ งานวิจัยและวิเคราะห์ ตลอดจนเป็นความเห็นส่วนตัวของผู้เขียนเอง ไม่ใช่ความเห็นของสถาบันป้องกันควบคุมโรคเขตเมือง หรือคณะบรรณาธิการแต่ประการใด ผู้เขียนจำต้องรับผิดชอบต่อบทความของตน
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