FACTORS ASSOCIATED WITH MORTALITY IN PATIENTS DIAGNOSED WITH ACUTE PULMONARY EMBOLISM IN CHIANGRAI PRACHANUKROH HOSPITAL
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Abstract
BACKGROUND: Acute pulmonary embolism (Acute PE) has been demonstrated to be the third most common cause of death from cardiovascular diseases. This study aimed to identify factors associated with the mortality of patients diagnosed with PE, resulting in urgent treatment and decreased risk of mortality in these patients.
OBJECTIVE: To study factors associated with mortality in acute pulmonary embolism. Identify comorbidities of hypercoagulable state and causes of acute pulmonary embolism.
METHODS: Retrospective study of patients diagnosed with acute pulmonary embolism who were admitted to the medical department at Chiangrai Prachanukroh Hospital from 1st January 2016 to 31st December 2020.
RESULTS: 140 patients met the inclusion criteria. Massive PE represented 15% of all patients. Cancer was found in 40% of the patients. Acute respiratory failure was shown at 28% of the patients. There were 5% and 7% of the patients who developed chronic pulmonary embolism and pulmonary hypertension accordingly. Factors associated with mortality at 1 month after diagnosis were calculated by multivariate analysis and illustrated that acute respiratory failure could significantly increase the risk of mortality with OR = 7.58, 95%CI = 2.27-25.29, P-value= 0.001.
CONCLUSIONS AND RECOMMENDATIONS: Acute respiratory failure increased the risk of death in acute pulmonary embolism patients. One should promptly be aware of this condition, prevent and immediately give patients treatment as soon as possible.
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