Can MTP decrease 24 hr mortality in Chiangrai Prachanukroh hospital ?

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Published: Dec 31, 2020
Keywords:
massive transfusion protocol mortality costs hospital stay

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vatchara kittijaroenwong
general surgery, Chiangrai prachanukroh hospital

Abstract

Background: hemorrhagic shock is cause of death in trauma patients. Massive transfusion protocol(MTP) have standard practice in multiple trauma centers. Several reports have discovered that MTP can reduced mortality in these patients. MTP started to use in February 2018 at Chiangrai Prachanukroh hospital. Therefore, this research was created to compare the pros and cons between before and after used MTP in hospital


Objective: primary outcomes were 24 hours mortality, 30 day mortality compared between before and after used MTP, secondary outcomes were costs, hospital stay, duration until first unit of blood to patients after to hospital, blood and component consumption in first 24 hours


Methods: A retrospective cohort study of trauma patients that had shock after fluid resuscitations 1-2 L, and had source of bleeding. Then divide in two group, first preMTP (1 January 2015-31 January 2018) and second (1 February 2018-March 2020). Data collection was reviewed from medical record. P value < 0.05 was considered  statistically significant.


Results: All 107 patients were eligible. PreMTP 48 patients , MTP 59 patients. No significant for general data such as sex, age, mechanism of injury, Glasgow coma score, severity of injury(PS score,ISS). When analysis of data found 24 hr mortality rate preMTP 19 patients(39.58%)/MTP 23 patients (38.98%) P value 0.55 odd ratio  1.04 95% confidence 0.46-2.36 p value 0.92, 30 day mortality rate preMTP 25 patients (52.08%)/MTP 26 patients (44.07%) p value 0.26 odd ratio 2.78 95% confidence 0.75-10.36 p value 0.12. There was no statistical difference in terms of costs, hospital stay, blood and components consumption in first 24 hours


Conclusions and discussions: MTP can slightly reduce the mortality rate, especially the first 30 days of mortality

Article Details

How to Cite
1.
kittijaroenwong vatchara. Can MTP decrease 24 hr mortality in Chiangrai Prachanukroh hospital ?. crmj [internet]. 2020 Dec. 31 [cited 2025 Dec. 12];12(3):33-45. available from: https://he01.tci-thaijo.org/index.php/crmjournal/article/view/245196
Issue
Vol. 12 No. 3 (2563): Chiangrai Medical Journal Edition 12 Volume 3 September - December
Section
Original Articles

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