Bacteremia and Antimicrobial Susceptibility of Clinical Isolates from Patients in Pathumthani Hospital: 2013-2018
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Abstract
Bacteremia is an important cause of hospital deaths. During 2013-2018, a total of 78,110 blood culture specimens in Pathumthani Hospital were cultured, 6,450 isolates (8.3%) were found positive cultures. Of which 57.1% were Gram-positive bacteria and 42.9% were Gram-negative bacteria. It was statistically significant difference when tested with Chi-square. The top five detected-bacteria were Methicillin-resistant Staphylococcus epidermidis (MRSE), Coagulase-negative staphylococcus, Escherichia coli, Staphylococcus aureus and Viridans group streptococci, with 21.2%, 16.4%, 13.9% 9.5% and 7.7%, respectively. Gram positive bacteria, MRSE were found and susceptible to Linezolid 96.0%, Vancomycin 92.5% but only 1.5% to Oxacillin. Among Gram negative bacteria, Escherichia coli was highly susceptible to Amikacin 97.9%. In the Carbapenem drug-group; Meropenem, Ertrapenem and Imipenem were highly susceptible, with 99.7%, 98.9% and 93.4%, respectively, but E. coli were low susceptible to Ampicillin only 20.3%. The rates of bacteremia and antimicrobial susceptibility pattern are essential and useful information for proper treatment and plan to hospital infection and prevention control.
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References
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