Prevalence of Helicobacter pylori Infection Among Cirrhotic Patients Undergoing Endoscopic Screening for Esophageal Varices at Lampang Hospital
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Abstract
Background: Helicobacter pylori (H. pylori) infection in patients with chronic liver disease has been associated with the exacerbation of complications. However, to date, no studies have assessed the prevalence and risk factors of H. pylori infection specifically in cirrhotic patients in Thailand.
Objective: To determine the prevalence of H. pylori infection and identify associated risk factors among cirrhotic patients.
Methods: A cross-sectional study was conducted at Lampang Hospital, including cirrhotic patients undergoing esophagogastroduodenoscopy (EGD) for esophageal varices screening. H. pylori infection was diagnosed using either a rapid urease test or histopathological examination. Patients were classified into H. pylori-infected and non-infected groups.
Results: Of the 108 cirrhotic patients included in the study, 32 (29.6%) were diagnosed with H. pylori infection. Alcoholic cirrhosis was the most common etiology, followed by cirrhosis due to hepatitis B virus and hepatitis C virus. Univariate analysis revealed no significant associations between the examined risk factors and H. pylori infection in cirrhotic patients.
Conclusion: Among cirrhotic patients undergoing EGD for esophageal varices screening, the prevalence of H. pylori infection was 29.6%.
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บทความที่ส่งมาลงพิมพ์ต้องไม่เคยพิมพ์หรือกำลังได้รับการพิจารณาตีพิมพ์ในวารสารอื่น เนื้อหาในบทความต้องเป็นผลงานของผู้นิพนธ์เอง ไม่ได้ลอกเลียนหรือตัดทอนจากบทความอื่น โดยไม่ได้รับอนุญาตหรือไม่ได้อ้างอิงอย่างเหมาะสม การแก้ไขหรือให้ข้อมูลเพิ่มเติมแก่กองบรรณาธิการ จะต้องเสร็จสิ้นเป็นที่เรียบร้อยก่อนจะได้รับพิจารณาตีพิมพ์ และบทความที่ตีพิมพ์แล้วเป็นสมบัติ ของลำปางเวชสาร
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