Role of bronchial washing and bronchial brushing in bronchosopic diagnosis of lung cancer

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Worapoth Lueangjiranothai


Objective: T evaluate the diagnostic yield of bronchial washing and bronchial brushing in addition to forceps biopsy for the
pathological diagnosis of lung cancer.

Material and method: A retrospective review of bronchoscopy cases for investigation of lung cancer in Lampang Hospital vetween January 2002 and December 2006 was done. All 820 cases were classified into 3 groups according to bronchoscopic findings (1) endrobronchial mass (2)endobronchial abnomality of abnormal bronchial mucosa and (3) normal bronchial mucosa. Statistical analysis of the data was performed by using the likelihood-ratio chi-square test.

Results: A significant increase in the diagnostic yield for lung cancer was seen when bronchial washing were added
to forceps biopsy only in endrobronchial abnormality group (43.5% VS 50.2%, p=0.01) akd when bronchial brushing were added to forceps biopsy only in endobronchial mass group. (68.4% VS 89.5%, p=0.027)

Conclusion: The addition of bronchial washing or bronchial brushing to forceps biopsy is beneficial when performed only in selected cases.


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Lueangjiranothai, W. (2022). Role of bronchial washing and bronchial brushing in bronchosopic diagnosis of lung cancer. Lampang Medical Journal, 28(1), 53–62. Retrieved from
Original Article


Udaya BS. Bronchoscopy. In: Mason RJ, Broaddus VC, Murray JF, Nadel JA, editors. Textbook of respiratory medicine. 4 th ed. Philadelphia: Elsevier Saunders, 2005. p. 617-50.

Govert JA, Kopita JM, Matchar D, Kussin PS, Samuelson WM. Cost-effectiveness of collecting routine cytological specimens during fiberoptic bronchoscopy for endoscopically visible lung cancer tumor. Chest. 1996;109(2):451-6.

Jones AM, Hanson IM, Armstrong GR, O'Driscoll BR. Value and accuracy of cytology in addition to histology in the diagnosis of

lung cancer at flexible bronchoscopy. Respir Med. 2001;95(5):374-8.

Kawaraya M, Gamba K, Ueoka H, Nishii K, Kiura K, Kodani T, et al. Evaluation of various cystological examinations by bronchoscopy

in diagnosis of peripheral lung cancer. Br J Cancer. 2003;89(10):1885-8.

Karahalli E, Yilmaz A, Turker H, Ozvaran K. Usefulness of various diagnosis techniques during fiberoptic bronchoscopy for endoscopically visible lung cancer: should cytologic examinations be performed routine? Respiration. 2001;68(6):611-4.

Soler TV, Isamitt DD, Carassco OA. Yield of biopsy, bronchial washing through fiberbronchoscopy in the diagosis of lung cancer with lesions. Rev Med Chi. 2004;132(10):1198-203.

Liwsrisakun C, Pothirat C, Bumroongkit C, Deesomchok A. Role of bronchial washing in the diagnosis of endoscopically visible lung cancer. J Med Assoc Thai. 2004;87(6):600-4.

Pederson U, Balle VH, Greison O. Diagnostic value of brush biopsy in suspected bronchial carcinoma with the use of the flexible fibre bronchoscope.

Clin Otolaryngol Alied Sci.1981;6(5):329-33.

Lam WK, So Sy, Hdu V, Yu DY. Fibreoptic bronchoscopy in the diagnosis

of bronchial cancer: comparison of washings, brushings and biopsies in central and peripheral tumours. Clin Oncol. 1983;9(1):35-42.

Fauzi AR, Balakrishnan L, Rathor MY. Usefulness of cytological speciments from bronchial brushings and bronchial washings in addition to endobronchial biopsies during bronchoscopy for lung

cancer: 3 years data from a chest clinic in a general hospital. Med J Malaysis. 2003;58(5):729-34.