A Randomized prospective Study of Fusion Rate Between Bone Marrow Aspirate Mixed Local Bone vs. Autologous Iliac Crest Bone Graft for Instrumented Posterolateral Fusion of Lumbar Spine

Abstract

A randomized controlled trial in posterolateral fusion in forty spondylolisthetic patients was performed to compare fusion rate between bone marrow aspirate mixed local bone and autologous iliac crest bone graft. All patients were operated vy single orthopaedic surgeon with the same technique and instrument. Fusion rates were evaluated by an independent doctor at 12th month post operation by plain radiographs. Devided all patientss to be two groups continuously. The first group was 85% (17 in 20 patients) and 90% (18 in 20 patients) in the second group but no statistically significant difference (p>0.05). The first group had no complication but three patients in the second group had donor harvest site morbidities (1 pain and 2 fractures) but no statistically
significant difference (p>0.05). Donor site pain was disappeared after 3 months later and iliac crest fractures in two patients did not affect activities daily living. Finally, posterolateral fusion in spondylolisthetic patients could achived by bone marrow aspirate mixed local bone comparable to autologuos iliac crest bone graft.