The Study of Practice Pattern and Quality of Life in the Use of Golden Turmeric Cannabis Oil Formula among Patients at Thai Traditional Medical Cannabis Clinics in Healthcare Facilities in Public Health Region 8

Main Article Content

Poramate Kinggo

Abstract

Golden Turmeric Cannabis Oil (GTCO) recipe is a medicinal cannabis-based formula certified by the Department of Thai Traditional and Alternative Medicine, Ministry of Public Health, for use in medical treatment or research. This quasi-experimental research aimed to explore the drug prescribing characteristics, quality of life and adverse reactions of GTCO users, among outpatients who received treatment at Thai traditional medicine clinics in 32 hospitals in Public Health Region 8 during November 2021–October 2022, and were followed up in the 1st and 3rd months of treatment. Data were collected using the R8-COT program. The results of data analysis showed that among 224 patients who were prescribed GTCO, 56.25% were women with a mean age of 53 ± 13.35 years. The formula was prescribed for migraine (46.88%), pain (29.02%), insomnia (16.96%) and other symptoms, including psoriasis, cancer, Parkinson’s and allergies (7.14%). The recommended starting dosage ranged from 2–3 drops per day, but mostly the patients received 2 drops once a day at bedtime; and most of them did not receive dose adjustments (92.86%). The second and third doses were adjusted to 3 drops/day (73.21% and 81.70%, respectively). The quality of life values after 3 months of treatment, based on the Edmonton Symptom Assessment Scale (ESAS) and data collected from the EQ-5D-5L questionnaire, showed that the mean utility value increased significantly (p-value < 0.001), compared to before treatment. In conclusion, Golden Turmeric Cannabis Oil improves the quality of life of patients. And it is safe even if there are adverse reactions, but they are not serious. Therefore, it can be considered as an alternative treatment for patients.

Article Details

Section
Original Articles

References

Pojanasin P. “Hemp or Kanchong”, a quality fiber plant that extends to economic crops [Internet]. 2017 [cited 2022 oct 1]. Available from: http://doa.go.th/hort/wp-content/uploads/2019/11/เฮมพ์หรือกัญชง-พืชเส้นใยคุณภาพ.pdf (in Thai)

Sripanidkulchai B. Medical Uses of cannabis. Isan Journal of Pharmaceutical Sciences. 2019;15(4):1-26. (in Thai)

Narcotics Control Division Food and Drug Administration. Medicinal cannabis recipes produced by ajaro hospital [Internet]. 2017 [cited 2022 oct 1]. Available from: https://cannabis.fda.moph.go.th/arjarohospital/

Ministry of Public Health. Medical cannabis [Internet]. 2017 [cited 2022 June 1]. Available from: https://www.medcannabis.go.th/ผลิตภัณฑ์กัญชาทางการแพทย์/ตำรับยากัญชาแผนไทย (in Thai)

Public Health Ministerial Declaration in 2021 on formulation of narcotics in the category 5 containing mixed cannabis that can be used for medicinal purposes or research studies 2021. Royal Gazette No.138, Part 35D (sup) (Feb 15, 2021). (in Thai)

Huaikoeng hospital. Guidelines for cannabis oil treatment in Thai traditional medical canabis clinics. 1. Udonthani: 2019. (in Thai)

Sawasdichai C, Im-iam S. Review of research on Thai herbs Thai traditional medicine and thai herbs. JPMC. 2016;33(3):265-70. (in Thai)

National Bureau of Agricultural Commodity and Food Standards, Ministry of Agriculture and Cooperatives. Certification scheme for organic agricuture [Internet]. [cited Jan 15, 2022]. Available from: www.acfs.go.th/files/files/attach-files/753_20190604102535_688912.pdf

Chirawatkul A. Biostatistics. 4th ed. KhonKaen university: Department of Biostatistics and Demography Faculty of public health; 2007. (in Thai)

Chinda M, Jaturapatporn D, Kirshen AJ, Udomsubpayakul U. Reliability and validity of a Thai version of the Edmonton Symptom Assession Scale (ESAS-Thai). J Pain Symptom Manage. 2011;42(6):954-60. doi: 10.1016/j.jpainsymman.2011.02.020. (in Thai)

Pattanaphesaj J. Health-related quality of life measure (EQ-5D-5L): measurement property testing and its preference-based score in Thai population (thesis). Pharmacy administration, Faculty of Graduate Studies. Bangkok: Mahidol University; 2014. (196 p.). (in Thai)

Health Product Vigilance Center. Health Product Adverse Event Report Form [Internet]. 2022 [cited 2022 June 1]. Available from: https://hpvcth.fda.moph.go.th/hpvc-form-1-แบบรายงานเหตุการณ์/ (in Thai)

Silarak K. Efficacy of cannabis oil (Deji’s formula) sleep quality and quality of life at Hang Ga Rok Clinic: Phra Arjarn Phan Arjaro hospital, Sakhon Nakhon province. RHPC9Journal. 2022;16(3):1097-108. (in Thai)

Lueangchiranothai P, Palawong S, Kamol T. Effectiveness of cannabis extract at medical cannabis clinic in Lampang hospital. J Thai Trad Alt Med. 2021;19(1):19-33. (in Thai)