Preliminary Effects of Prasaplai Capsule for Menstruation Disorder Treatment

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Ratree Sawangjit
Nuttakarn Nuntalard
Prapatsron Pradakorn
Ruchilak Rattarom


Prasaplai is a Thai traditional herbal medicine in the National List of Essential Herbal Medicines used for the treatment of abnormal menstruation. However, there is no current clinical evidence to support the efficacy of Prasaplai on this indication. The aim of this study was to monitor the effects of Prasaplai on abnormal menstruation treatment in women who bought Prasaplai at Mahasarakham University drug store in order to treat their symptoms. The data were collected using questionnaires to evaluate clinical signs and symptoms before and after Prasaplai use for 1 week, 4 weeks (the 1st menstrual cycles), and 9 weeks (the 2nd menstrual cycles) in 24 women aged between 23.9 ± 1.3 years old. All of the subjects took 1-2  Prasaplai capsules (Prasaplai extract 250 mg/capsule) 3 times a day before meals. 70% of the subjects (17 individuals) suffered from oligomenorrhea. After Prasaplai administration, abnormal menstruation was cured in 7 persons and increased to 12 persons in the 1st and the 2nd menstrual cycles, respectively. There was no evidence of adverse drug reactions to Prasaplai. In conclusion, this study indicated that Prasaplai may be an effective and safe for treatment of abnormal menstruation. However, randomized controlled trials should be further performed to confirm the efficacy and safety of Prasaplai for this indication.


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