Volume Calibration of “Tha-nan”and the effects in the efficacy of drugs preparation
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Abstract
“Tha-nan” in Thai traditional scriptures was different from “tha-nan luang”, the latter being a unit of volume equivalent to 1 liter. “Tha-nan luang” was used to measure out crude drugs for preparing medicines instead of traditional “tha-nan”, which might affect prepared drugs’ efficacy. The objective of this study was to calibrate the volume of traditional tha-nan and to evaluate the efficacy of wound-healing remedies prepared using calibrated tha-nan, compared with those prepared using tha-nan luang, in healing excision wounds on male Spraque-Dawley rats. The calibrated volume of “tha-nan” was calculated by multiplying the traditional “tha-nan” size number with 1.548, the converting factor, to obtain the volume in milliliters. The efficacy evaluation of the prepared wound-healing remedies showed that the oil remedies prepared with crude drugs measured out using the calibrated tha-nan (NR119/78cv) of 929 milliliters based on “tha-nan 600” and the balm remedy prepared with crude drugs measured out using the calibrated tha-nan (WP255/2cv) of 1,285 milliliters based on “tha-nan 830” were more efficacious than those prepared with crude drugs measured out using tha-nan luang.
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References
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