Botanical Identification of Chan-thet and Chan-hom Crude Drugs by Thin Layer Chromatography

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Uthai Sotanaphun
Sununta Srisopon
Jankana Burana-osot


"Chan-thet" and "chan-hom" are crude drugs whose identifications are confusing; so their botanical
species should be investigated. Fifteen samples of crude drugs çchan-theté and 11 samples of "chanhom"
were randomly purchased from traditional drugstores throughout Thailand. Their chemical
fingerprints were investigated using the thin layer chromatography method. The results were compared
with authentic samples, and a-santalol purified in our laboratory was used as the chemical marker. The
results indicated that all samples of "chan-thet" and 9 samples of "chan-hom" possessed a-santalol as
their chemical constituent. Among them, 11, 3 and 1 samples of "chan-thet" gave chemical fingerprints
similar to Santalum spicatum, S. album and S. lanceolatum, respectively; whereas 8 and 1 samples of
"chan-hom" were similar to those of S. spicatum and S. lanceolatum, respectively. Two other samples of
"chan-hom" revealed chemical fingerprints similar to Mansonia gagei. Based on the results, it is concluded
that "chan-thet" and "chan-hom" currently available in traditional drugstores originate from
four different plant species, mostly from the wood of S. spicatum. And the results can be applied for the
quality control of "chan-thet" and "chan-hom" crude drugs.


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