Treatment outcomes and factors influencing unsuccessful outcomes among tuberculosis patients in Rattaphum District, Songkhla Province
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Abstract
Background: According to the tuberculosis patient reports from Ratphum Hospital for the fiscal years 2016 - 2021, the number of tuberculosis cases recorded were 36, 23, 34, 46, 42, and 27, respectively. More than 50% of these cases were patients who had previously been treated for tuberculosis and had relapsed. The objective of the study is to examine the treatment success rate and risk factors of unsuccessful pulmonary tuberculosis treatment outcomes in Ratphum District, Songkhla Province.
Methods: This study is a retrospective study that collected data from the medical records of tuberculosis patients over a 5-year period from 2016 to 2021. The sample group consisted of 208 individuals. The data were analyzed using descriptive statistics, including, percentage, mean, median, and standard deviation, as well as inferential statistics, including the Chi-square test or Fisher exact test and logistic regression analysis.
Results: The treatment failure rate was 18.7%. The factors significantly associated with treatment failure in tuberculosis patients in Ratphum District, Songkhla Province, at a significance level of 0.05 included HIV/AIDS, a history of previous tuberculosis treatment, the absence of directly observed therapy (DOT), the results of the first and second X-rays, sputum microscopy results in months 2, 5, and 6 of diagnosis, and drug susceptibility testing for tuberculosis medications (Streptomycin, Isoniazid, Rifampicin, Ethambutol).
Conclusions: The treatment failure rate was 18.7%. Factors associated with treatment failure in tuberculosis patients included HIV/AIDS, a history of previous tuberculosis treatment, the absence of directly observed therapy (DOT), X-ray results, sputum microscopy, and drug susceptibility testing for tuberculosis medications.
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