Comparison of Pregnancy and Birth Outcomes of Pregnant Women Before and During the COVID-19 Pandemic at Khon Kaen Hospital

Authors

  • Kanokporn Wannapong Faculty of Nursing, Khon Kaen University
  • Somjit Muangpin Faculty of Nursing, Khon Kaen University
  • Thiwawan Thepa Faculty of Nursing, Khon Kaen University
  • Tanyalak Wongluecha Khon Kaen Hospital
  • Pranee Namhanual Khon Kaen Hospital

Keywords:

COVID-19, birth outcomes, pregnancy outcomes

Abstract

This analytic study employed an unmatched case-control design to compare pregnancy and birth outcomes among women who delivered before and during the COVID-19 pandemic at Khon Kaen Hospital. Data were extracted from the maternity records of Khon Kaen Hospital. The sample was divided into two groups: 1) the control group was comprised of 2,550 women who gave birth before the COVID-19 pandemic with delivery dates recorded in the health register database between March 25, 2018 and March 25, 2020 and 2) the study group which was comprised of 2550 women who gave birth during the COVID-19 pandemic with delivery dates recorded between March 26, 2020 and July 1, 2022. Data collection utilized a checklist questionnaire addressing demographic characteristics, antenatal care, pregnancy, and delivery outcomes with a content validity index of 0.93. Binary logistic regression was employed to examine differences in outcomes between the groups.

The results revealed that women who delivered during the COVID-19 pandemic had a lower likelihood of experiencing preterm birth; however, they faced a higher prevalence of postpartum hemorrhage. The control group had fewer prenatal visits. Neonatal outcomes in the study group indicated a trend toward rate of low birth weight infants than control group, a reduced incidence of neonatal hypoxia, and fewer admissions to the neonatal intensive care unit. Nevertheless, neonatal-maternal separation occurred more frequently during the pandemic. These findings can be applied to improve maternal care systems, enhance monitoring obstetric complications, and prepare healthcare services for the management of future emerging diseases incidents.

Downloads

Download data is not yet available.

References

Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, Biswas A, et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. American Journal of Obstetrics and Gynecology. 2020;222(6):521–31. doi:10.1016/j.ajog.2020.03.021

Wu H, Sun W, Huang X, Yu S, Wang H, Bi X, et al. Online antenatal care during the COVID-19 pandemic: Opportunities and challenges. Journal of Medical Internet Research. 2020;22(7):e19916. doi:10.2196/19916

Rabbani U, Saigul AA, Sulaiman A, Ibrahim TH. Impact of COVID-19 on antenatal care utilization among pregnant women in Qassim, Saudi Arabia. Cureus. 2021;13(11):e19554. doi:10.7759/cureus.19554

Goyal M, Singh P, Singh K, Shekhar S, Agrawal N, Misra S. The effect of the COVID-19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. International Journal of Gynecology and Obstetrics. 2021;152(2):231–5. doi:10.1002/ijgo.13457

Golbasi H, Omeroglu I, Bayraktar B, Golbasi C, Adıyaman D, Ekin A. How COVID-19 pandemic is changing the practice of prenatal screening and diagnosis? Journal of Perinatal Medicine. 2022;50(2):124–31. doi:10.1515/jpm-2021-0343

Golbasi H, Bayraktar B, Golbasi C, Omeroglu I, Adiyaman D, Sever B, et al. Can sonographic imaging of the fetal pancreas predict perinatal outcomes in gestational diabetes mellitus? Journal of Perinatal Medicine. 2022;50(9):1189–1197. doi:10.1515/jpm-2022-0050

Ministry of Public Health. Manual for summarizing causes of maternal and child death. [Internet]. 2022 [cited 2025 May 20]. Available from: http://medinfo2.psu.ac.th/medrec/mediplus-lite/uploads/Cause_of_death.pdf (in Thai)

Health Center 7 Khon Kaen. Guidelines for maternal and child health operations in Health Region 7. [Internet]. 2022 [cited 2025 May 20]. Available from: http://203.157.71.148/data/cluster/mom /download/ManualMCH63.pdf (in Thai)

Weigel G, Frederiksen B, Ranji U, Salganicoff A. Screening and intervention for psychosocial needs by U.S. obstetrician-gynecologists. Journal of Women's Health. 2022;31(6):887–94. doi:10.1089/jwh.2021.0236.

Wang N, Deng Z, Wen LM, Ding Y, He G. Understanding the use of smartphone apps for health information among pregnant chinese women: Mixed methods study. JMIR mHealth and uHealth. 2019;7(6):e12631. doi:10.2196/12631.

Ranjbar F, Allahqoli L, Ahmadi S, Mousavi R, Gharacheh M, Eshraghi N, et al. Changes in pregnancy outcomes during the COVID-19 lockdown in Iran. BMC Pregnancy Childbirth. 2021;21(1):577. doi:10.1186/s12884-021-04050-7

Simeone RM, Downing KF, Wallace B, Galang RR, DeSisto CL, Tong VT, et al. Changes in rates of adverse pregnancy outcomes during the COVID-19 pandemic: A cross-sectional study in the United States, 2019–2020. Journal of Perinatology. 2022;42(5):617–23. doi:10.1038/s41372-022-01327-3

Du M, Yang J, Han N, Liu M, Liu J. Association between the COVID-19 pandemic and the risk for adverse pregnancy outcomes: A cohort study. British Medical Journal Open. 2021;11(2):e047900. doi:10.1136/bmjopen-2020-047900

Wen J. Impact of COVID-19 pandemic on birth outcomes: A retrospective cohort study in Nanjing, China. Frontiers in Public Health. 2022;10:923324. doi:10.3389/fpubh.2022.923324

Giesbrecht GF, Rojas L, Patel S, Kuret V, Mackinnon AL, Tomfohr-Madsen L, et al. Fear of COVID-19, mental health, and pregnancy outcomes in the pregnancy during the COVID-19 pandemic study: Fear of COVID-19 and pregnancy outcomes. Journal of affective disorders. 2022;299:483-91. doi:10.1016/j.jad.2021.12.057

World Health Organization. WHO chief declares end to COVID-19 as a global health emergency. [Internet]. 2023 [cited 2025 May 20]. Available from: https://news.un.org/en/story/2023/05/1136367

Ngamjaras C. Sample size calculation for health science research. Khon Kaen: Center for Learning and Teaching Innovation, Khon Kaen University; 2021. (in Thai)

Calvert C, Brockway MM, Zoega H, Miller EJ, Been JV, Amegah AK, et al. Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries. Nature Human Behavior. 2023;7:529-44. doi:10.1038/s41562-023-01522-y

Daskalakis G, Psarris A, Koutras A, Fasoulakis Z, Prokopakis I, Varthaliti A, et al. Maternal infection and preterm birth: From Molecular Basis to Clinical Implications. Children (Basel). 2023;10(5):907. doi:10.3390/children10050907

Townsend R, Chmielewska B, Barratt I, Kalafat E, van der Meulen J, Gurol-Urganci I, et al. Global changes in maternity care provision during the COVID-19 pandemic: A systematic review and meta-analysis. eClinicalMidicine. 2021;37:100947. doi:10.1016/j.eclinm.2021.100947.

Durankuş F, Aksu E. Effects of the COVID-19 pandemic on anxiety and depressive symptoms in pregnant women: A preliminary study. Journal of Maternal-Fetal and Neonatal Medicine. 2022;35(2):205–11. doi:10.1080/14767058.2020.1763946

Chalermpichai T, Subsomboon K, Kasak R, Pinitlertsakun O, Pangzup S. Factors influencing the antenatal care attendance of pregnant women during the first COVID-19 wave lockdown in Thailand. International journal of women's health. 2023;15:731-40. doi:10.2147/IJWH.S409642.

Januszewski M, Santor-Zaczynska M, Ziuzia-Januszewska L, Kudan M, Jakimiuk AA, Wierzba W, et al. Postpartum blood loss in COVID-19 patients-propensity score matched analysis. Biomedicines. 2022;10(10):2517. doi:10.3390/biomedicines10102517.

Barchi L, Braibanti S, Gargano G. The post-pandemic re-organization of birth centres and its impact on perinatal asphyxia in the province of Reggio Emilia. International Journal of Gynecology and Obstetrics. 2023;35:69. doi:10.36129/jog.2022.S68

Janthasing S. Factors associated with birth asphyxia with one minute Apgar score of 7 or less in Buayai Hospital, Nakhonratchasima Province. Medical Journal of Sisaket Surin Buriram Hospitals. 2022;35(3):679–88. (in Thai)

Downloads

Published

2026-01-22

How to Cite

1.
Wannapong K, Muangpin S, Thepa T, Wongluecha T, Namhanual P. Comparison of Pregnancy and Birth Outcomes of Pregnant Women Before and During the COVID-19 Pandemic at Khon Kaen Hospital. J Nurs Ther Care [internet]. 2026 Jan. 22 [cited 2026 Jan. 23];44(1):e281011. available from: https://he01.tci-thaijo.org/index.php/jnat-ned/article/view/281011