Concordance and Accuracy of Cervical Cytology and LEEP pathological In Chaophrayayomarat Hospital Suphanburi province
Keywords:
Concordance, Accuracy, Colposcopy results, Pathology results, Cervical cancerAbstract
Abstract
Objective: The aim of this was to determine the concordance and accuracy of colposcopic biopsy with abnormal cervical cytology in Suphanburi provience, Thailand.
Method of study: The retrospective descriptive study was performed by collecting data in medical record period October,1 2015 - September,30 2017 who resister Gynelogical out patient In Chao Phraya Yomarat Hospital who has been report of specimen 220 patients with abnormal pap smear ,cervical cytology who went a colposcopy guided cervical biopsy and subsequent LEEP analyzed. Data was analyzed using descriptive statistic , kappa statistic and validity
Results: The mean age was 42 years. Fertility period 117 (77.7%), Multiparous 201 (91.4%). The Concordance rate between a cervical cytology and LEEP histopathological was 88.63% with kappa coefficient, Weight Kappa was substantial (0.65) and significantly (t=100.17, p=<0.05). Accuracy had sensitivities of 72.55% and specificitives of 92.90%
Conclusion: The Concordance rate between a cervical cytology and LEEP histopathological was 88.63 % with kappa coefficient, Weight Kappa was substantial (0.65). Accuracy had sensitivities of 72.55% and specificitives of 92.90%
Keywords: colposcopy; Loop Electrosurgical Excision Procedure(LEEP);CIN; Cervical cancer Screening.
References
World Health Organization.Cervical cancer.[Internet]. 2016.[cited 2018 July 30].Available from https://www.who.int/cancer/preventi on/diagnosis-screening/cervical- cancer/en/
Thailand Human Papilloma virus and Related Cancers, Fact Sheet 2018.
[Internet].2018.[cited 2018 January 30]. Available from https://hpvcentre.net/statistics/reports/THA_FS.pdf.
จตุพล ศรีสมบูรณ์. การดูแลจัดการผลเซลล์วิทยา ปากมดลูกผิดปกติปีพ.ศ.2560.2560. [อินเตอร์เน็ต].[วันที่อ้างถึง 15 สิงหาคม 2562].ที่มา. https://www.chiangmaihealth.go.th › cmpho_web › document.
Butchaihong P. Update American Cancer Society Guidelines for Screening Cervical Cancer 2011. [Internet]. 2011 .[cited 2018 June 30]. Available fromhttp://www.med.cmu.ac.th/dept /obgyn/2011/index
Saslow D et al. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. CA Cancer J Clin.2012; 62(3): 147-72.
สำนักงานกองทุนสนับสนุนการสร้างเสริมสุขภาพ. ตั้งเป้าหญิงไทยตรวจมะเร็งปากมดลูก.
[อินเตอร์เน็ต].2555.[วันที่อ้างถึง 15 สิงหาคม 2562]. ที่มา http://www.thaihealth.or.th/Content/ 29409.html. 7. สำนักนโยบายและยุทธศาสตร์ สำนักงาน ปลัดกระทรวงสาธารณสุข.สรุปสถิติที่สำคัญ
พ.ศ. 2559. [อินเตอร์เน็ต]. 2559. [วันที่อ้างถึง15 สิงหาคม 2562].ที่มา
https://www.mciety.go.th/ewtadmin/ewt/mso_web/article_attach/18956/2052 7.pdf6.
สำนักงานสาธารณสุขจังหวัดสุพรรณบุรี. สถิติ สำนักงานสาธารณสุขจังหวัดสุพรรณบุรี 2560.[อินเตอร์เน็ต]. 2560. [วันที่อ้างถึง 15 สิงหาคม 2562, ที่มา http://www.spo.go.th/sso/uthong.
โรงพยาบาลเจ้าพระยายมราช. งานเวชระเบียน และสถิติ.รายงานประจำปีแผนกสูตินรีเวช 2559.สุพรรณบุรี : โรงพยาบาล, 2559
Campion MJ. Cervical cancer screening and preinvasive disease. In:Berek, J.S.,Hacker, N.F(eds). Berek &Hacher’s gynecologic oncology (6th ed).(pp. 242-325). Philadelphia: Wolters Kluwer; 2010.
Soutter WP et al. Invasivecervical cancer after conservative therapy forCervical intraepithelial neoplasia.Lancet (London, England).1997; 349(9057): 978-980.
Ferris DG et al . Modern colposcopy Textbook and atlas.(2 nd). (pp.244-249).Iowa: Kendall/Hunt Publishing; 2004.
Massad LS et al. 2012 updated consensus guidelines for the management of tests and cancer precursors.J Low Genit Tract Dis. 2013; 17(3): 367.
Faul F, Erdfelder E, Lang A.-G, Buchner A. G*Power 3: A flexible statistical power analysis program for the social, behavioral, andbiomedical sciences. Behavior Research Methods.2007; 39, 175-191.
Solomon D et al. The 2001 Bethesda system: terminology for reporting results of cervical cytology.JAMA. 2002; 287:2114-9.
Boonlikit S et al. Correlation between colposcopically directed biopsy and large loop excision of the transformation zone and influence of age on the outcome. Journal of The Medical Association of Thailand.2006; 89:299–305.
Zuchna C et al. Diagnostic accuracy of guided cervical biopsies: a p rospective multicenter study comparing the histopathology of simultaneous biopsy and cone specimen. American Journal of Obstetrics and Gynecology.2010;
: 321–326.
Stoler MH et al. The accuracy of colposcopic biopsy: analyses from the placebo arm of the Gardasil clinical trials. International Journal of Cancer.2011; 128:1354–1362.
Jain V, Vyas AS. Cervical Neoplasia-Cyto- Histological Correlation (Bethesda System) A Study of 276 Cases. J CytolHistol.2010.1:106.doi:10.4172/21 57-7099.1000106
Vyas VJaA. Cervical neoplasia–Cyto– Histological Correlation(Bethesda System) A Study of 276 cases. J CytolHistol. 2010; 1(106):1–3.
Amir Asotic ST, Jasmina Asotic. Correlation of Cervical Smear and Pathohistological Findings. Med Arh. 2014; 68:106–9.
Kahramanoglu I et al. The use of colposcopic punch biopsy in the management of abnormal cervical cytology: a 5–year retrospective audit Journal of Obstetrics and Gynaecology. 2019; 39( 1): 110–114.
Duesing N et al. Assessment of cervical intraepithelial neoplasia (CIN) with Colposcopic biopsy and efficacy of loop electrosurgical excision procedure (LEEP). Arch Gynecol Obstet. 2012 ; 286(6):1549-1554.
เกื้อหนุน บัวไพจิตร. ความสัมพันธ์ของผลการ ตรวจคัดกรองมะเร็งปากมดลุกกับผลการ ตรวจทางพยาธิในโรงพยาบาลสกลนคร. วารสารโรงพยาบาลสกลนคร 2561; 21(3) : 1-11.
Muruka K et al . Same day colposcopic examination and loop electrosurgical excision procedure (LEEP) presents minimal overtreatment and averts delay in treatment of cervical intraepithelial neoplasia in Kenyatta National Hospital, Kenya.Open Journal of Obstetrics and Gynecology.2013; 3 :313-318.
Kahramanoglu I. et al. The use of colposcopic punch biopsy in the management of abnormal cervical cytology: a 5–year retrospective audit. Journal of Obstetrics and Gynaecology. 2019; 39(1): 110-114.
Yuyeon J et al. Clinical factors that affect diagnostic discrepancy between colposcopically directed biopsies and loop electrosurgical excision procedure conization of the uterine cervix.Obstet Gynecol Sci. 2018; 61(4): 477-488.
Zhang L et al. Discrepancies between biopsy-based and excision-based grading of cervical intraepithelial neoplasia: the important role of time between excision and biopsy. Int J Gynecol Pathol. 2015; 34: 221-227.
Giannella L et al. High-grade CIN on cervical biopsy and predictors of the subsequent cone histology results in women undergoing immediate conization. Eur J Obstet Gynecol Reprod Biol.2015; 186: 68-74.
Rodriguez-Manfredi A et al. HPV genotyping among women treated for high-grade cervical intraepithelial neoplasia with no lesion in the conization specimen. Int J Gynaecol Obstet. 2015; 129(2):109-113.
Nam K et al . Clinical significance of a negative loop electrosurgical excision procedure biopsy in patients with biopsy confirmed high-grade cervical intraepithelial neoplasia. J Low Genit Tract Dis. 2015; 19(2):103-109.
Noothong S et al. Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia Taiwanese Journal of Obstetrics & Gynecology .2017; 56: 628-631.
Li ZG et al. Three-step versus “see-and- treat” approach in women with high-grade squamous intraepithelial lesions in a low-resource country. Int J Gynaecol Obstet. 2009; 106: 202-205.
Ostor AG. Natural history of cervical intraepithelial neoplasia: a critical review.Int J Gynecol Pathol .1993; 12:186-192.
Nasiell K et al. Behavior of moderate cervical dysplasia during long-term follow-up. Obstet Gynecol. 1983; 61:609-614.
Castle PE et al. Evidence for frequent regression of cervical intraepithelial neoplasia-grade 2. Obstet Gynecol .2009;113:18-25.
Ryu A et al. Absence of dysplasia in the excised cervix by a loop electrosurgical excision procedure in the treatment of cervical intraepithelial neoplasia. J Gynecol Oncol. 2010; 21:87-92.
Kyrgiou M et al. The up-to-date evidence oncotposcopy practice and treatment of cervicaIintraepithetiaIneoplasia: theCochrane colposcopy &cervical cytopathologycot[aborative group (C 5 group).2006.
ปิยวัฒน์ เลาวหุตานนท์, อาคม ชัยวีระวัฒนะ, วีรวุฒิ อิ่มสำราญ.แนวทางการตรวจคัดกรอง วินิจฉัยและรักษาโรคมะเร็งปากมดลูกปี 2560. กรุงเทพมหานคร:โฆสิตการพิมพ์; 2560.
Moss EL et al. The diagnostic accuracy of colposcopy in previously treated cervical intraepithelialneoplasia. Journal of Lower Genital Tract Disease. 2009; 13: 5–9.
Zuchna C et al. Diagnostic accuracy of guided cervical biopsies : a prospective multicenter study comparing the histopathology of simultaneousbiopsy and cone specimen. American Journal of Obstetricsand Gynecology.2010; 203:321–326.
Feng-Yi Xiao et al. Diagnostic Accuracy of Colposcopically Directed Biopsy and Loop Electrosurgical Excision Procedure for Cervical Lesions. Reproductive and Developmental Medicine. 2018; 2(3) ;137.
Ouitrakul S et al. Accuracy of Colposcopically Directed Biopsy in Diagnosis of Cervical Pathology at Srinagarind Hospital. Asian Pacific journal of cancer prevention: APJCP.2011; 12(9): 2451-3.
Downloads
Published
How to Cite
Issue
Section
License
บทความที่ได้รับการตีพิมพ์ในวารสารหัวหินเวชสาร เป็นลิขสิทธิ์ของโรงพยาบาลหัวหิน
บทความที่ลงพิมพ์ใน วารสารหัวหินเวชสาร ถือว่าเป็นความเห็นส่วนตัวของผู้เขียนคณะบรรณาธิการไม่จำเป็นต้องเห็นด้วย ผู้เขียนต้องรับผิดชอบต่อบทความของตนเอง
