Prevalence and Risk factors for Opisthorchiasis in Nakhamin Sub-District, Phonsawan District, Nakhon Phanom Province, Thailand
Main Article Content
Abstract
Opisthorchis viverrini causes a major health problem especially in the northeast and north of Thailand. Therefore, this study aimed to investigate the prevalence of O. viverrini infections and factor related to O. viverrini infections. A cross-sectional study was conducted between May and August 2020 in the Nakhamin sub-district, Phon Sawan district, Nakhon Phanom province, Thailand. Total 250 stool samples were collected using Kato's thick smear technique to determine the prevalence of helmiths infections and the questionnaire were collected to investigate the knowledge, attitude, practice and also investigated the factor which correlated with O. viverrini infection.
The overall intestinal helminthes infection were 23.2%, the prevalence of O. viverrini and Enterobius vermicularis was 22.0 % and 1.2%, respectively. In addition, the factors related to opisthorchiasis were sex, age (40-60 years old), and eating raw fish at p-value <0.05. The result suggests that O. viverrini still significant endemic in rural community. Therefore, the intervention program should be implemented in this area.
Article Details
References
Keiser J and Utzinger J. Food-borne trematodiases. Clin Microbiol Rev 2009; 22(3): 466-83. doi: 10.1128/CMR.00012-09.
Sripa B, Kaewkes S, Sithithaworn P, Mairiang E, Laha T, Smout M, et al. Liver Fluke Induces Cholangiocarcinoma. PLoS Med 2007; 4(7). doi: 10.1371/journal.pmed.0040201.
Sithithaworn P , Andrews RH, Nguyen VD, Wongsaroj T, Sinuon M, Odermatt P, et al. The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitol Int 2012; 61(1): 10-16. doi: 10.1016/j.parint.2011.08.014.
Laoraksawong P, Sanpool O, Rodpai R, et al. Current high prevalences of Strongyloides stercoralis and Opisthorchis viverrini infections in rural communities in northeast Thailand and associated risk factors. BMC Public Health 2018; 18(1): 940. doi: 10.1186/s12889-018-5871-1.
Enes JE, Wages AJ, Malone JB, Tesana S. Prevalence of Opisthorchis viverrini infection in the canine and feline hosts in three villages, Khon Kaen province, Northeastern Thailand. Southeast Asian J Trop Med Public Health 2010; 41(1): 36–42.
Khuntikeo, N. and Yongvanit, P. Conceptual framework of health policy and strategies to administer and manage cholangiocarcinoma systematically and effectively. Srinagarind Medical Journal 2012; 27(suppl): 422-26. (in Thai)
Thaewnongiew K , Singthong S, Kutchamart S, Tangsawad S, Promthet S, Sailugkum S, Wongba N. Prevalence and risk factors for Opisthorchis viverrini infections in upper Northeast Thailand. Asian Pac J Cancer Prev 2014; 15(16): 6609-12. doi: 10.7314/apjcp.2014.15.16.6609.
Sithithaworn P, Andrews RH, Nguyen VD, et al. The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitol Int 2012; 61(1): 10-6.
Nakbun S, Thongkrajai P, Nithikathkul C. Risk factors for Opisthorchis viverrini infection in Nakhon Phanom, Thailand, where the infection is highly endemic. Asian Biomed (Res Rev News) 2018; 12(1): 45–51.
Sayasone S, Meister I, Andrews JR, Odermatt P, Vonghachack Y, Xayavong S, et al. Efficacy and Safety of Praziquantel Against Light Infections of Opisthorchis viverrini: A Randomized Parallel Single-Blind Dose-Ranging Trial. Clin Infect Dis 2017; 64: 451-8.
Bunchu N , Vitta A , Thongwat D , Lamlertthon S , Pimolsri U, Waree P. Enterobius vermicularis Infection among Children in Lower Northern Thailand. J Trop Med Parasitol 2011; 34: 36-40.
Suwannahitatorn P, Klomjit S, Naaglor T, Taamasri P, Rangsin R, Leelayoova S, et al. A follow-up study of Opisthorchis viverrini infection after the implementation of control program in a rural community, central Thailand. Parasites & vectors 2013; 6: 1-8.
Rangsin R, Mungthin M, Taamasri P, Mongklon S, Aimpun P, Naaglor T, et al. Incidence and Risk Factors of Opisthorchis viverrini Infections in a Rural Community in Thailand. Am. J. Trop. Med. Hyg 2009; 81: 152-5.
Chuangchaiya S, Laoprom N, Idris, ZM. Prevalence and associated risk factors of Opisthorchis viverrini infections in rural communities along the Nam Kam River of Northeastern Thailand. Tropical Biomedicine 2019; 36(1): 81-93.
Khan-Ngern K., Kritsanakarn, O., and Silawong, K. The level of knowledge, attitude and consumption behavior of raw fish of people in Pho Sub-District, Muang District, Sisaket Province. Journal of Srivanalai Vijai 2011; 1(2): 76-87. (in Thai)
Painsing S., Sripong A, Vensontia O, Pengsaa P., Kompor P., Kootanavanichapong N., et al. Health Behavior Regarding Liver Flukes among Rural People in Nakhon Ratchasima, Thailand. Asian Pac J Cancer Prev 2016; 17: 2111-4.
Chokwanitchpong, W., Sarakan, U. and Sangrajrang, S. Study of behaviors and attitudes related to eating raw freshwater fish and cholangiocarcinoma. Thai Cancer Journal 2009; 29(4): 162-175. (in Thai)
Saenna P, Hurst C, Echaubard P, Wilcox BA, Sripa B. Fish sharing as a risk factor for Opisthorchis viverrini infection: evidence from two villages in north-eastern Thailand Infect Dis Poverty 2017; 6: 66. doi: 10.1186/s40249-017-0281-7.
Suwannahitatorn P, Webster J, Riley S, Mungthin M, Donnelly CA. Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand. PLoS ONE 2019; 14(1): e0211540. doi: 10.1371/journal.pone.0211540.