基于 CiteSpace 和 VOSviewer 百会穴现代文献研究现状和发展趋势的可视化分析

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陈 泽权
林 卓鹏

摘要

作为督脉要穴,百会穴 (DU20)“调神”作用尤为突出,其相关研究文献虽数量庞大,但脉络失于梳理,故本研究基于中国知网(CNKI)2000 年 1 月至 2023 年 8 月期间的文献,运用 CiteSpace 与 VOSviewer 软件进行知识图谱可视化分析,以探究百会穴的研究现状、热点及发展趋势,以期为其进一步研究提供参考。经筛选共纳入基础研究文献 727 篇和临床研究文献 2,207 篇,结果显示,基础研究领域形成了以邹伟、陈立典、孙国杰为代表的三个团队,临床研究领域则以黄泳、庄礼兴、杨骏为核心形成三个研究团队,现有研究主要围绕百会穴的刺激方法、穴位配伍及疗效展开。本研究提示,未来百会穴基础研究应着力于深化“调神”的细胞分子机制与构建基于数据挖掘的临床精准配穴方案,并增强临床预见性、构建“反向转化” 通道、发展更贴近人类的疾病模型,以推动基础与临床的深度融合。

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参考

Fang ZT, Chen YJ, Xu YD, Yin LM, Yang YQ, Wang Yu. On the inheritance, challenges and innovative development of acupuncture and moxibustion medicine. Shanghai Journal of Traditional Chinese Medicine. 2022;56(6):3-6. (in Chinese)

Merigó JM, Gil-Lafuente AM, Yager RR. An overview of fuzzy research with bibliometric indicators. Applied Soft Computing. 2015;27:420-33.

Ding XD. Fundamentals of bibliometrics. Beijing: Peking University Press; 1993. (in Chinese)

Zou W, Niu MM, Yu XP, Sun XW, Teng Wei, Dai XH, et al. Effect of Baihui-Qubin acupuncture therapy on PERK protein expression in intracerebral hemorrhage rat models. Information on Traditional Chinese Medicine. 2017;34(2):75-9. (in Chinese)

Guan RQ, Zou W, Yu XP, Sun XW, Dai XH, Teng W, et al. Expression of CD62p in acute cerebral hemorrhage rats intervened by acupuncture of Baihui-to-Qubin. Acta Chinese Medicine and Pharmacology. 2017;45(4):74-8. (in Chinese)

Xu WT, Xue YM, Wang C, Kong Y, Zou W. Mechanism study of needling GV20 through GB7 in inhibiting neurological function injury in rats with ICH by regulating EGFR/STAT3 pathway. Journal of Clinical Acupuncture and Moxibustion. 2022;38(7):70-5. (in Chinese)

Kong Y, Duan HC, Liu Y. Study of penetration acupuncture on p-STAT3 of cerebral hemorrhage rats’ brain tissues after JNK pathway inhibition. Journal of Emergency in Traditional Chinese Medicine. 2017;26(11):1895-8. (in Chinese)

Li L, Huang S, Li L, Zhang JY, Jin TT, Zhang YH, et al. Effects of electroacupuncture on brain function of APP/PS1 mice: a functional magnetic resonance imaging study. Chinese Journal of Rehabilitation Theory and Practice. 2020;26(5):544-9. (in Chinese)

Huang J, Song CM, Yang MG, Li JH, Huang S, Liu WL, et al. Effects of electroacupuncture at Baihui and Shenting on learning and memory and expression of purinoceptor P2X7 in hippocampal CA1 after cerebral ischemia-reperfusion in rats. Chinese Journal of Rehabilitation Theory and Practice. 2018;24(1):43-8. (in Chinese)

Tang SH, Du YJ, Xiao JH, Wang Y, Shen F, Sun GJ. Acupuncture and moxibustion improves learning-memory ability of Alzheimer’s disease rats possibly by up-regulating serum Aβ internalization enzyme contents. Acupuncture Research. 2018;43(11):692-7. (in Chinese)

Huang Y, Lai XS. Effects of needling in Baihui, Shuigou and Shenmen on regional cerebral blood flow in vascular dementia patients. China Journal of Traditional Chinese Medicine and Pharmacy. 2006;21(8):462-4. (in Chinese)

Huang Y, Lai XS, Chen J, Tang AW, Li DJ. Effect of acupuncture at Baihui, Shuigou and Shenmen on thalamic glucose metabolism in vascular dementia patients. Chinese Journal of Rehabilitation Medicine. 2006;21(6):501-3. (in Chinese)

Lai XS, Huang Y, Tang CZ, Yang JJ. A study on cerebral lobes’ glucose metabolism in vascular dementia patients treated by DU20, DU26 and HT7. Chinese Journal of Basic Medicine in Traditional Chinese Medicine. 2006;12(5):375-7. (in Chinese)

Huang Y, Chen J, Lai XS, Tang AW, Li DJ. Effects of needling in Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) on glucose metabolism in the lentiform nucleus in patients with vascular dementia. Academic Journal of the First Medical College of PLA. 2005;(11):1405-7. (in Chinese)

Li YM, Zhuang LX, Li YH. Observations on the efficacy of pressing moxibustion on point Baihui (GV 20) plus acupuncture at cervical Huatuojiaji (Ex-B2) points in treating cervical vertigo. Shanghai Journal of Acupuncture and Moxibustion. 2012;31(2):112-3. (in Chinese)

Xu SF, Zhuang LX. Observations on the efficacy of electroacupuncture at Baihui and Yintang as main treatment for depression. Shanghai Journal of Acupuncture and Moxibustion. 2010;29(9):569-72. (in Chinese)

Xu SF, Zhuang LX, Yin P, Wu JY, Cao Y. Evaluation of clinical efficacy of heart and spleen deficiency type insomnia treated by acupuncture for regulating governor vessel and tranquilizing spirit. Journal of Guangzhou University of Traditional Chinese Medicine. 2016;33(1):31-4. (in Chinese)

Cha BX, Yang J. Professor Yang Jun's experience in treating cervical vertigo with moxibustion at Baihui acupoint. Shanghai Journal of Acupuncture and Moxibustion. 2014;33(9):790-1. (in Chinese)

Li SC Yang J, Fan YQ, Zhang YT, Liu WT, Chen RR, et al. Professor Yang Jun’s experience in treating vascular dementia with moxibustion for removing blood stasis and unblocking meridians. 2024 annual conference proceeding of the China Association for Acupuncture and Moxibustion; 2024 Sep 27, Shehuishan Conference Resort Hotels, Tianjin. Beijing: China Association for Acupuncture and Moxibustion; 2024. 2065-9. (in Chinese)

Zhu CF, Yang J, Cai SC, Pan HP, He CG, Liang MJ. Randomized controlled clinical trials for moxibustion therapy on DU meridian of vascular mild cognitive impairment. Liaoning Journal of Traditional Chinese Medicine. 2019;46(1):132-5. (in Chinese)

Chavez LM, Huang SS, MacDonald I, Lin JG, Lee YC, Chen YH. Mechanisms of acupuncture therapy in ischemic stroke rehabilitation: a literature review of basic studies. Int J Mol Sci. 2017;18(11):2270.

Lei XL. Effect of electroacupuncture combined with repetitive transcranial magnetic stimulation on cognitive impairment after stroke [dissertation]. Wuhan: Hubei University of Chinese Medicine; 2022. (in Chinese)

Wang Y, Wang J. Research progress on the treatment of apoplexy sequelae with long-time needle retaining at Baihui (GV20). Clinical Journal of Traditional Chinese Medicine. 2022;34(8):1559-63. (in Chinese)

Song YJ, Zhang DQ, Zhao YH. Effect of long- stayed scalp cluster- needling in intermittent lines on body function recovery and daily life ability of patients with cerebral infarction. Acta Chinese Medicine and Pharmacology. 2015;43(6):69-71. (in Chinese)

Wei KX, Huang CL, Chen XP, Cao H. Effects of electrical acupuncturing in Baihui acupoint on sleep phases of post-traumatic stress disorder rats and the mechanisms. Shaanxi Journal of Traditional Chinese Medicine. 2019;40(10):1333-5. (in Chinese)

Yuan HL, Yang BY. Overview of clinical application of Baihui (DU20) acupoint. Journal of Practical Traditional Chinese Medicine. 2021;37(12):2138-41. (in Chinese)

Jia YM. Effects of the serum amino acid neurotransmitter by acupuncture Baihui, Sishencong in insomniac. Chinese Journal of Medicinal Guide. 2016;18(6):567-8. (in Chinese)

Xian YM, Liang YA, Zhu LH, Huang KB. Curative effect observation on electroacupuncture for depression after ischemic stroke of liver Qi depression type and Qi deficiency and blood stasis type. Journal of New Chinese Medicine. 2018;50(9):185-7. (in Chinese)

Liu RL. Clinical study of electric acupuncture Shenting and Baihui point on mild cognitive impairment after stroke. Clinical Research and Practice. 2017;2(29):101-2. (in Chinese)

Qin XY, Zhang BS, Zhang XJ, Lu XT, Liu HX, Wang CN. Effect of electroacupuncture on inflammation response and ferroptosis in rats modeling postoperative cognitive dysfunction. Chinese General Practice. 2024;27(6):723-32. (in Chinese)

Peng W, Zhou J, Xu M, Feng Q, Bin LL, Liu ZS. The effect of electroacupuncture combined with donepezil on cognitive function in Alzheimer’s disease patients: study protocol for a randomized controlled trial. Trials. 2017;18(1):301.

Shang H, Li YH, Ran LC, Song YW, Wang YJ. Rules of acupoints selection in treatment of perimenopausal insomnia by using modern literature research and data mining. Journal of Clinical Acupuncture and Moxibustion. 2023;39(2):60-7. (in Chinese)

Liu BY. Liberate thoughts, innovate mechanisms, and plan a large-scale scientific research program on acupuncture. Chinese Acupuncture and Moxibustion. 2017;37(1):1. (in Chinese)

Pan WX. Preface: calling for research on translational acupuncture. Acupuncture Research. 2023;48(1):1-2. (in Chinese)

Koshimizu H, Hazama S, Hara T, Ogura A, Kojima M. Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons. Neurosci Lett. 2010;473(3):229-32.

Shi RX, Li H, Liu NG, Yu ZG, Tang XZ. Impact of needling points group of Yintang (EX-HN3) - Baihui (DU20) - Fengchi (GB20) - Shenshu (BL23) on expression of hippocampus brain-derived neurotrophic factor gene of chronic stress model rats. Journal of Traditional Chinese Medicine. 2017;58(21):1860-3. (in Chinese)

Yang L, Liao MF, Ji XR, Jing ZP. Current research of superoxide dismutase in the medical field. Progress in Modern Biomedicine. 2010;10(2):396-8. (in Chinese)

Chen SF, Chen YJ, Feng Y, Wu P, Cui CL. Association of serum superoxide dismutase level with cardiac and renal function in elderly patients. Journal of Tongji University (Medical Science). 2019;40(5):618-23. (in Chinese)

Ma YD, Sun XW, Hu XY. Effects of electrical stimulation to acupoints on cognitive function and oxidative stress in post-stroke rats. Journal of Clinical Acupuncture and Moxibustion. 2022;38(10):76-80. (in Chinese)