基于数据挖掘探讨中医治疗糖尿病视网膜病变的常用药物规律

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刘 美莹
陈 文恬
陈 欣蔚
林 冠文

摘要

本文旨在使用文献数据挖掘,探讨十年来中医治疗糖尿病视网膜病变(DR)的常用药物规律。我们使用与糖尿病视网膜病变、中药、中医和糖尿病眼病等常用相关的关键词,于 CNKI、PubMed、ScienceDirect 和 Springer Link 数据库中进行了文献搜索,将符合纳入标准的文献被录入 Microsoft Excel 和 IBM SPSS Modeler 订阅版进行频率分析和关联规则分析。在纳入的 25 篇治疗 DR 的论文中,一共涉及 102 种中药,其中治疗 DR 最常用的中药是地黄、黄芪和当归,常见的中药组合包括黄芪和地黄、地黄和当归、黄芪和川芎。最常用的中药大多具有活血、益气和滋阴的功能,这研究结果表明 DR 基本上具有“气阴不足,血瘀阻络”的潜在病因病理机制,因此在治疗 DR 时应考虑采用补益气阴,疏通血瘀,濡养眼睛的药物。

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