多酚防治骨质疏松症的作用机制研究进展
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摘要
骨质疏松症是一种常见的慢性骨骼疾病，表现为骨脆性和骨折风险增加，严重影响患者生活质量，寻找有效的预防和治疗策略至关重要。多酚是一类广泛存在于植物中的天然活性物质，具有抗氧化、抗炎等多种生理活性。多项研究发现多酚可通过抗氧化、抗炎、促进骨形成和抑制骨吸收等机制调节骨代谢过程，且其相较于常用药物具有多效与天然无毒可持续的优势，故对骨质疏松的预防和治疗具有良好的潜在价值。本文就近年来多酚防治骨质疏松症的机制研究作一综述，旨在为开发多酚类化合物作为防治骨质疏松症的潜在药物提供理论依据和新思路。
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