The Preparation of the Positive List of Thai Traditional Medicine Formulas Based on Priority Setting

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Pitsaphun Werayingyong
Ketwaraporn Wongprim
Chavisa Praditukrit
Kornrawee Kornwisitwathin

Abstract

The preparation of the ‘Positive List of Thai Traditional Medicine Formulas’ was first carried out during the
fiscal year 2019 for the manufacturers to use as a reference when applying for permission to manufacture listed Thai Traditional Medicine formulas or preparations (TTMP) using a listing method, based on the Herbal Products Act B.E. 2562 (2019). The selection of TTMP for inclusion in the positive list is based on the priority setting principle. This article aims to share experiences in the application of the priority setting method for selecting and including a TTMP in the first version of the Positive List which makes the TTMP selection an evidence-based, systematic and transparent approach. Initially, the selection criteria in health care issues were reviewed, gathered and weighed. The weight and scores of the four main selection criteria were then determined, namely 1) efficacy, 2) safety, 3)quality control, and 4) others, i.e. the number of herbal ingredients in the TTMP, whether the TTMP help solve national health problems, and domestic availability of the herbal materials. The scoring of each TTMP was therefore evidence-based and verifiable. However, as it has been known, the availability of evidence regarding efficacy and safety of most TTMP was limited and only a long history of use could be taken into account. Meanwhile, the quality control data was available more for crude drugs than for TTMP. Hence, due to the limitation of the evidence, the selection criteria for TTMP inclusion in the Positive List may need to be revised using an evidence-based approach to the selection of potential TTMP for further research to determine their efficacy, safety and quality. In addition, all stakeholders should get involved in the selection process in order to have TTMP that meet the demand of the users and the manufacturers.

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