Clinical Study of Chanta-lee-la Herbal Herbal Household Remedy

Abstract

Chanta-lee-la, one of the famous Thai traditional herbal formulas, consists of nine herbs: Kot So [Angelica dahurica Benth.], Kot Kamao [Atractylodes lancea (Thunb.)DC.], Kot Chula-lumpa [Artemisia annua L.], Kadom [(Gymnopetalum cochichinense (Lour.) Kurz], Chanthet [Santalum album L.], Chandaeng
[Pterocarpus santalinus L.f.], Boraphet [Tinospora crispa (L.) Miers ex Hook.f.&Thoms.] and Phalai Phueak [Eurycoma longifolia Jack], four parts each, and a part of Phimsen (Borneo camphor). Although this remedy is commonly used as an antipyretic drug at doses of 500 mg to 1 gram every four hours, the clinical trial for effective fever clearance and safety profile has not yet been done. This research was a prospective study in patients with the common cold who had met the eligibility inclusion/exclusion criteria. Eighteen patients were enrolled, with a mean oral temperature before being given the medication, of 38.7°C 0.7. Follow-up at 4 hours later found the mean oral temperature to be 38.4°C 0.8 and found decreased to no fever statistically significant levels when compared with hour 0 and hour 16 with a mean oral temperature of 37.4°C 0.8 (p <0.001). Even though this study indicated decreased fever over a longer period of time than drugs currently used, for safety reasons, the trial herbal recipe did not cause any serious adverse event. The adverse events that were observed in 77.8 percent of the cases were symptoms related to the common cold