Seroprevalence of Hepatitis B and C Virus Infections and Related Risk Factors of Hepatitis B Virus Infection among Newly Diagnosed Tuberculosis Patients at National Tuberculosis Program (Central), Mandalay Office, Myanmar
Keywords:
Hepatitis B, Hepatitis C, Risk factors, Seroprevalence, TuberculosisAbstract
Objective: To study the seroprevalence of hepatitis B and C virus infections and related risk factors of hepatitis B virus infection among newly diagnosed tuberculosis patients.
Materials and Methods: This cross-sectional descriptive study was done at Outpatient Department (OPD), National Tuberculosis Program (Central), Mandalay Office from 1st May 2019 to 31st August 2019. A total of 200 newly diagnosed patients were tested for HBsAg and anti-HCV and knowledge, attitude, and preventive practice against hepatitis B were interviewed using pre-tested, structured questionnaires.
Results: In this study, hepatitis B or C prevalence was 9.5% (95%CI:5.43 to 13.57) and prevalence of HBsAg was 4.5% (95%CI:1.6 to 7.4), and anti-HCV was 5% (95%CI:1.95 to 8.05) among newly diagnosed tuberculosis patients. Prevalence is higher in the age above 40 years, and male patients, and low education levels, resided in other cities. Generally, 93% of patients had a good attitude, but 55.5% had poor knowledge of hepatitis B infection. Knowledge level was statistically significantly associated with the education level of patients (χ2=20.418, p value=<0.001). Histories of taking injections without necessary and dental procedures un-screening were risk factors for the occurrence of HBsAg.
Conclusion: The prevalence of hepatitis was high among newly diagnosed tuberculosis patients. All TB patients should be screened for hepatitis before starting anti-TB treatment. Nationwide health education programs for hepatitis should be promoted according to the education status of patients.
Keywords: Hepatitis B, Hepatitis C, Risk factors, Seroprevalence, Tuberculosis
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