Seroprevalence of Hepatitis B and C Virus Infections and Related Risk Factors of Hepatitis B Virus Infection among Newly Diagnosed Tuberculosis Patients at National Tuberculosis Program (Central), Mandalay Office, Myanmar

Authors

Keywords:

Hepatitis B, Hepatitis C, Risk factors, Seroprevalence, Tuberculosis

Abstract

Objective: To study the seroprevalence of hepatitis B and C virus infections and related risk factors of hepatitis B virus infection among newly diagnosed tuberculosis patients.

Materials and Methods: This cross-sectional descriptive study was done at Outpatient Department (OPD), National Tuberculosis Program (Central), Mandalay Office from 1st May 2019 to 31st August 2019. A total of 200 newly diagnosed patients were tested for HBsAg and anti-HCV and knowledge, attitude, and preventive practice against hepatitis B were interviewed using pre-tested, structured questionnaires.

Results: In this study, hepatitis B or C prevalence was 9.5% (95%CI:5.43 to 13.57) and prevalence of HBsAg was 4.5% (95%CI:1.6 to 7.4), and anti-HCV was 5% (95%CI:1.95 to 8.05) among newly diagnosed tuberculosis patients. Prevalence is higher in the age above 40 years, and male patients, and low education levels, resided in other cities. Generally, 93% of patients had a good attitude, but 55.5% had poor knowledge of hepatitis B infection. Knowledge level was statistically significantly associated with the education level of patients (χ2=20.418, p value=<0.001). Histories of taking injections without necessary and dental procedures un-screening were risk factors for the occurrence of HBsAg.

Conclusion: The prevalence of hepatitis was high among newly diagnosed tuberculosis patients. All TB patients should be screened for hepatitis before starting anti-TB treatment. Nationwide health education programs for hepatitis should be promoted according to the education status of patients.

Keywords: Hepatitis B, Hepatitis C, Risk factors, Seroprevalence, Tuberculosis

Downloads

Download data is not yet available.

References

World Health Organization. WORLD HEPATITIS DAY 2014. [Internet] 2014. [Cited 2019 April 3]. Available from: https://www.who.int/campaigns/hepatitis-day/2014/hepatitis-b-c-d.pdf?ua=1

World Health Organization. Contagion Liver, Infectious Diseases Today, WHO Reports Global Burden of Viral Hepatitis Is Increasing. [Internet] 2017. [Cited 2019 April 3] Available from: https://www.contagionlive.com/news/who-reports-global-burden-of-viralhepatitis-is-increasing.

Centers for Disease Control and Prevention. Hepatitis B Questions and Answers for the Public. [Internet] 2018. [Cited 2019 February 15]. Available from: https://www.cdc.gov/features/worldhepatitisday/

Averhoff, F.M., Glass, N. & Holtzman, D. Global Burden of Hepatitis C: Considerations for Healthcare Providers in the United States. Clinical Infectious Diseases 2012; 55(suppl_1), S10–S15.

World Health Organization, South-East Asia Region. World Health Organization, Burden of Viral Hepatitis in the South-East Asia Region. [Internet] 2015. [Cited 2019 April 4]. Available from: http://www.searo.who.int/hepatitis/data/hepatitis_data_statistics/en/

Zampino, R., Boemio, A., Sagnelli, C., Alessio, L., et al. Hepatitis B virus burden in developing countries. World Journal of Gastroenterology 2015; 21 (42),11941–11953.

Ministry of Health and Sports. Myanmar National Action Plan for Viral Hepatitis Response 2017- 2020. Myanmar. MOHS 2017.

Hepatitis B Free. Hepatitis B. [Internet] 2018. [Cited 2019 February 16]. Available from: https://hepatitisbfree.org.au/current-projects/myanmar/

Aye Aye Lwin. Sero-prevalence of Hepatitis B and C Viral Infections in Myanmar: National and Regional Survey in 2015, Myanmar Health Sciences Research Journal 2015; 29,(3)2017.

World Health Organization. World Hepatitis Day, Test. Treat. Hepatitis. [Internet] 2018. [Cited 2017 February 17]. Available from: https://www.who.int/campaigns/world-hepatitis-day/2018

WHO/CDS/TB. World Health Organization, Global tuberculosis report. Geneva, World Health Organization 2018.

World Health Organization, South-East Asia Region. World Health Organization, Burden of Viral Hepatitis in the South-East Asia Region. [Internet] 2015. [Cited 2019 April 4]. Available from: http://www.searo.who.int/hepatitis/data/hepatitis_data_statistics/en/

Caminero JA. A tuberculosis guide for specialist physicians. Paris: International Union Against Tuberculosis and Lung Disease. 2004.

Asian Liver Center. What is hepatitis B? [Internet] 2019. [Cited 2019 February 17]. Available from: http://med.stanford.edu/liver/education/whatishepb.html

Datz C, Cramp M, Haas T, Dietze O, Nitschko H, Froesner G, Muss N, Sandhofer F, Vogel W. The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a plasmapheresis centre. Gut. 1999;44(4):563-7.

Centers for Disease Control and Prevention. Hepatitis B Questions and Answers for the Public. [Internet] 2018. [Cited 2019 February 15]. Available from: https://www.cdc.gov/features/worldhepatitisday/

Rajamoorthy Y, Taib NM, Munusamy S, Anwar S, Wagner AL, Mudatsir M, Müller R, Kuch U, Groneberg DA, Harapan H, Khin AA. Knowledge and awareness of hepatitis B among households in Malaysia: a community-based cross-sectional survey. BMC Public Health. 2019;19(1):1-1.

Yau AH, Ford JA, Kwan PW, Chan J, Choo Q, Lee TK, Kwong W, Huang A, Yoshida E. Hepatitis B awareness and knowledge in Asian communities in British Columbia. Canadian Journal of Gastroenterology and Hepatology. 2016.

Taylor VM, Tu SP, Woodall E, Acorda E, Chen H, Choe J, Li L, Yasui Y, Hislop TG. Hepatitis B knowledge and practices among Chinese immigrants to the United States. Asian Pacific Journal of Cancer Prevention. 2006;7(2):313.

Elbur A, Almalki N, Alghamdi A, Alqarni Alqarni H. Knowledge, attitude and practice on Hepatitis B: A survey among the internet users in Taif, Kingdom of Saudi Arabia. J Infect Dis Epidemiol. 2017;3(3):1-7.

Khairkhah T, Shamsa A, Roohi A, Khoshnoodi J, Vand-Rajabpour F, Tabrizi M, Zarei S, Golsaz-Shirazi F, Shokri F. Analysis of knowledge, attitudes, and prevalence of hepatitis B and C seromarkers among barbers in Tehran. Hepatitis monthly. 2016 Sep;16(9).

Published

2022-05-21

How to Cite

1.
Aung T, Khaing W. Seroprevalence of Hepatitis B and C Virus Infections and Related Risk Factors of Hepatitis B Virus Infection among Newly Diagnosed Tuberculosis Patients at National Tuberculosis Program (Central), Mandalay Office, Myanmar. J. Med. Glob. [Internet]. 2022 May 21 [cited 2023 Feb. 9];1(1):36-4. Available from: https://he01.tci-thaijo.org/index.php/JMedGlob/article/view/256489

Issue

Section

Original Article