Main Article Content
Older persons with chronic illness require continuing and long term medication therapy. Therefore, medication adherence is important for them because it associated with the effective of treatment, reducing severity of disease, improving quality of life, reducing mortality, and costs. However, older persons with chronic illness still poor medication adherence. Nurses, who are the one in health care team have important role to help them improve medication adherence. Although, there are various studies about medication adherence. But, the studies about the medication adherence in older persons with chronic illness were limited. These studies were focused on specific study in some chronic diseases. Moreover, they defined medication adherence in different ways. In this paper, the authors have conducted literature review on researches and articles of medication adherence in older persons with chronic illness. This review article covers: 1) the definition and components of medication adherence, 2) medication adherence in older persons with chronic illness, 3) factor affecting medication adherence measuring medication adherence including social and economic factors, health care team and system-related factors, condition-relate factors, therapy-relate factors, and patient-related factors, 4) assessing medication adherence by using objective measurement and subjective measurement, and 5) guideline for improving medication adherence. Nurse can use this guideline to promote medication adherence in older persons with chronic illness.
United Nations, Department of Economic and Social Affairs, Population Division. World population ageing 2015. New York: United Nations; 2015.
Department of Older Persons, Ministry of Social Development and Human Security. Situation of the Thai older 2018. [Internet]. [cited 2019 October 11]. Available from: https://www.dop.go.th/th/know/1.
Chiewchantanakit D, Kiatying-Angsulee N, Sirisinsuk Y. Medication use situation in Thai elderly: the computerized database from four tertiary care hospitals. Thai Journal of Hospital Pharmacy 2013;23(1):9-20. (in Thai).
Thongcharoen V. Science and art gerontological nursing. 2nd ed. Bangkok: NP Press; 2015. (in Thai).
Marengoni A, Monaco A, Costa E, Cherubini A, Prados-Torres A, Muth C, et al. Strategies to improve medication adherence in older persons: consensus statement from the Senior Italia Federanziani Advisory Board. Drugs Aging 2016;33(9):629-37.
Chutitorn A. Medication adherence in clients with chronic illness. Thai Red Cross Nursing Journal 2013;6(2):25-34. (in Thai).
Khlaihong W, Jitramontree N, Wirojratana V. Factors predicting medication adherence behaviors among older adults with type 2 diabetes. The Journal of Faculty of Nursing Burapha University 2016;24(1):65-75. (in Thai).
Rungsawang S. Factors related to polypharmacy medication adherence among older persons with chronic illness. Journal of Nursing, Siam University 2017;18(35):6-23. (in Thai).
Kumpiriyapong N, Sasat S. The effect of health belief programme on medicine used behavior in older persons with hypertension. Royal Thai Navy Medical Journal 2017;44(3):67-83. (in Thai).
Ruangthip T, Wattanakitkrileart D, Charoenkitkarn V, Dumavibhat C. Factors influencing medication adherence in patients with chronic heart failure. Royal Thai Navy Medical Journal 2017;44(3):51-65. (in Thai).
Suwannapong K, Thanasilp S, Chaiyawat W. Medication adherence in persons with coronary artery disease: a delphi study. Journal of Health Research 2016;30(3):149-54.
World Health Organization. Adherence to long-term therapies: evidence for action. Geneva: WHO; 2003.
Cramer JA, Roy A, Burrell A, Fairchild CJ, Fuldeore MJ, Ollendorf DA, et al. Medication compliance and persistence: terminology and definitions. Value Health 2008;11(1):44-7.
Dunbar-Jacob J, Bohachick P, Mortimer MK, Sereika SM, Foley SM. Medication adherence in persons with cardiovascular disease. J Cardiovasc Nurs 2003;18(3):209-18.
Rungrojwatanasiri P, Soonthornchaiya R, Upasen R. The effect of group social support program on medication adherence of elderly patients with major depressive disorder. The Journal of Psychiatric Nursing and Mental Health 2017;31(1):119-32.
Sasang N, Chusak T, Sootthasil M. Self-care behaviors of the diabetes elderly with complications of kidney disease, Phaisalee district, Nakorn-Sawan provice. Journal of Safety and Health 2017;10(36):46-52. (in Thai).
Thanomsat K, Tapasee W. The study of drug compliance behaviors model of elders with hypertension in community. Area Based Development Research Journal 2015;7(2):36-49. (in Thai).
Chaichanawirote U, Vithayachockitikhun N. Medication use behaviors among older Thai adults. Journal of Nursing and Health Sciences 2015;9(1):32-46. (in Thai).
Darunthanom W, Utaipiboon C, Tangchitphisut P. Medication use adherence and behaviors among elderly patients with chronic diseases in Tambom Hua Ngom, Phan district, Chiangrai province. Chiangrai Medical Journal 2019;11(1):19-27. (in Thai).
Wongboonnak P, Wongtrakul P, Mahamongkol H, Neimkhum W. The survey of medicine, food supplement and herbal products used problems among elderly: a case study at the community of Tumbon Srisa Chorakhe Noi, Samut Prakan province. HCU Journal 2016;20(39):97-108. (in Thai).
Uchmanowicz B, Chudiak A, Uchmanowicz I, Rosinczuk J, Froelicher E. Factors influencing adherence to treatment in older adults with hypertension. Clinical Interventions in Aging 2018;13:2425-41.
Jin H, Kim Y, Rhie S. Factors affecting medication adherence in elderly people. Patient Prefer Adherence 2016;10:2117-25.
Roy N, Sajith M, Bansode M. Assessment of factors associated with low adherence to pharmacotherapy in elderly patients. Journal of Young Pharmacists 2017;9(2):272-6.
Park H, Seo S, Yoo H, Lee K. Medication adherence and beliefs about medication in elderly patients living alone with chronic diseases. Patient Preference and Adherence 2018;12:175-81.
Tepsuriyanont S. A causal model of medication adherence behavior among hypertensive adult patients. Journal of Nursing and Education 2017;10(1):1-15. (in Thai).
Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005;353(5):487-97.
Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens 2008;10(5):348-54.
Ingkamanee N, Kusuma Na Ayuthya S, Puwarawuttipanit W, Peerapatdit T. Effectiveness of promoting a problem-solving ability program on medication adherence in patients with type 2 diabetic. J Nurs Sci 2011;29(2):56-64.
Wongsuwan P. Development of instrument for keep taking medicine and motivation in taking medicine among elderly hypertension in community. Journal of Nursing and Education 2017;10(1):90-104.
Kim MT, Hill MN, Bone LR, Levine DM. Development and testing of the Hill-Bone Compliance to High Blood Pressure Therapy Scale. Prog Cardiovasc Nurs 2000;15(3):90-6.
Thompson K, Kulkarni J, Sergejew AA. Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophr Res 2000;42(3):241-7.
Suwannapong K, Thanasilp S, Chaiyawat W. The development of Medication Adherence Scale for persons with coronary artery disease (MAS-CAD): a nursing perspective. Walailak Journal of Science and Technology 2019;16(1):19-25.
Svarstad BL, Chewning BA, Sleath BL, Claesson C. The Brief Medication Questionnaire: a tool for screening patient adherence and barriers to adherence. Patient Educ Couns 1999;37(2):113-24.
Kripalani S, Risser J, Gatti ME, Jacobson TA. Development and evaluation of the Adherence to Refills and Medications Scale (ARMS) among low-literacy patients with chronic disease. Value Health 2009;12(1):118-23.
Suphachamroon A, Lerkiatbundit S, Saengcharoen W. Validity and reliability of the Medication Adherence Scalein Thais (MAST): testing in diabetes patients. Thai Journal of Pharmacy Practice 2019;10(2):607-19. (in Thai).
Strandbygaard U, Thomsen SF, Backer V. A daily SMS reminder increases adherence to asthma treatment: a three-month follow-up study. Respir Med 2010;104(2):166-71.
Bormann S, Sayorwan W, Channim S, Rungruangkhanarak S, Suksamran P, Srisuk P, et al. Effects of medication reminder innovation on adherence and the quality of medicine. The Public Health Journal of Burapha University 2018;13(2):117-25. (in Thai).
Limcharoen N, Wanishayakorm T, Lerkiatbundit. Effects of pictograms on how to take oral tablets in illiterate Thai muslim patients. Thai Journal of Pharmacy Practice 2017;9(2):294-306. (in Thai).
Moral RR, Torres LA, Ortega LP, Larumbe MC, Villalabos AR, Garcia JA, et al. Effectiveness of motivational interviewing to improve therapeutic adherence in patients over 65 years old with chronic diseases: a cluster randomized clinical trial in primary care. Patient Educ Couns 2015;98(8):977-83