Supplement & Eye Disease

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Napang Kedkovid




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1 .Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001;119(10):1417-36.

2. Chew EY, Clemons TE, Agrón E, Sperduto RD, Sangiovanni JP, Kurinij N, et al. Long-term effects of vitamins C and E, β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35. Ophthalmology 2013;120(8):1604-11.

3. Chew EY, Lindblad AS, Clemons T; Age-Related Eye Disease Study Research Group. Summary results and recommendations from the age-related eye disease study. Arch Ophthalmol 2009;127(12):1678-9.

4. Age-Related Eye Disease Study 2 Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA 2013;309(19):2005-15.

5. Tan JS, Wang JJ, Flood V, Rochtchina E, Smith W, Mitchell P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmology 2008;115(2):334-41.

6. Merle BMJ, Colijn JM, Cougnard-Grégoire A, de Koning-Backus APM, Delyfer MN, Kiefte-de Jong JC, et al. Mediterranean diet and incidence of advanced age-related macular degeneration: the EYE-RISK Consortium. Ophthalmology 2019;126(3):381-90.

7. Radak Z, Taylor AW, Ohno H, Goto S. Adaptation to exercise-induced oxidative stress: from muscle to brain. Exerc Immunol Rev 2001;7:90-107.

8. Khandhadia S, Lotery A. Oxidation and age-related macular degeneration: insights from molecular biology. Expert Rev Mol Med 2010 Oct 20;12:e34. doi: 10.1017/S146239941000164X.

9. McGuinness MB, Le J, Mitchell P, Gopinath B, Cerin E, Saksens NTM, et al. Physical activity and age-related macular degeneration: a systematic literature review and meta-analysis. Am J Ophthalmol 2017;180:29-38.

10. Hobbs BN. Eye health' supplements: do the benefits justify the cost?. [Internet]. [cited March 25, 2019]. Avialable from:

11. Nation Eye Institue. Facts about cataract. [Internet]. [cited March 25, 2019]. Avialable from:

12. Glaser TS, Doss LE, Shih G, Nigam D, Sperduto RD, Ferris FL 3rd, et al. The association of dietary lutein plus zeaxanthin and B vitamins with cataracts in the age-related eye disease study: AREDS report no. 37. Ophthalmology 2015;122(7):1471-9.

13. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 2001;119(10):1439-52.

14. Cumming RG, Mitchell P, Smith W. Diet and cataract: the blue mountains eye study. Ophthalmology 2000;107(3):450-6.

15. Cataracts: can vitamin supplements help maintain your vision?. [Internet]. [cited 2019 March 25]. Avialable from:

16. Neale RE, Purdie JL, Hirst LW, Green AC. Sun exposure as a risk factor for nuclear cataract. Epidemiology 2003;14(6):707-12.

17. Hayashi LC, Hayashi S, Yamaoka K, Tamiya N, Chikuda M, Yano E. Ultraviolet B exposure and type of lens opacity in ophthalmic patients in Japan. Sci Total Environ 2003;302(1-3):53-62.

18. Craig JP, Nichols KK, Akpek EK, Caffery B, Dua HS, Joo CK, et al. TFOS DEWS II definition and classification report. Ocul Surf 2017;15(3):276-83.

19. Wei Y, Asbell PA. The core mechanism of dry eye disease (DED) is inflammation. Eye contact lens 2014;40(4):248–56.

20. Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, et al. TFOS DEWS II epidemiology report. Ocul Surf 2017;15(3):334-65.

21. Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 2008;8(5):349-61.

22. Dry Eye Assessment and Management Study Research Group, Asbell PA, Maguire MG, Pistilli M, Ying GS, Szczotka-Flynn LB, et al. n-3 Fatty Acid supplementation for the treatment of Dry Eye Disease. N Engl J Med 20183;378(18):1681-90.

23. Ray PD, Huang BW, Tsuji Y. Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell Signal 2012;24(5):981-90.

24. Dogru M, Kojima T, Simsek C, Tsubota K. Potential role of oxidative stress in ocular surface inflammation and Dry Eye Disease. Invest Ophthalmol Vis Sci 2018 Nov 1;59(14):DES163-DES168. doi: 10.1167/iovs.17-23402.

25. Chen Y, Mehta G, Vasiliou V. Antioxidant defenses in the ocular surface. Ocul Surf 2009;7(4):176-85.

26. Pasquale LR, Kang JH. Lifestyle, nutrition, and glaucoma. J Glaucoma 2009;18(6):423–8.

27. Al Owaifeer AM, Al Taisan AA. The role of diet in glaucoma: a review of the current evidence. Ophthalmol Ther 2018;7(1):19-31.

28. Jiwani AZ, Rhee DJ, Brauner SC, Gardiner MF, Chen TC, Shen LQ, et al. Effects of caffeinated coffee consumption on intraocular pressure, ocular perfusion pressure, and ocular pulse amplitude: a randomized controlled trial. Eye (Lond) 2012;26(8):1122-30.

29. Wu CM, Wu AM, Tseng VL, Yu F, Coleman AL. Frequency of a diagnosis of glaucoma in individuals who consume coffee, tea and/or soft drinks. The British journal of ophthalmology 2018;102(8):1127-33.

30. Guo X, Kong X, Huang R, Jin L, Ding X, He M, et al. Effect of Ginkgo biloba on visual field and contrast sensitivity in Chinese patients with normal tension glaucoma: a randomized, crossover clinical trial. Invest Ophthalmol Vis Sci 2014;55(1):110-6.

31. Shim SH, Kim JM, Choi CY, Kim CY, Park KH. Ginkgo biloba extract and bilberry anthocyanins improve visual function in patients with normal tension glaucoma. J Med Food 2012;15(9):818-23.

32. Quaranta L, Bettelli S, Uva MG, Semeraro F, Turano R, Gandolfo E. Effect of Ginkgo biloba extract on preexisting visual field damage in normal tension glaucoma. Ophthalmology 2003;110(2):359-62.

33. Coleman AL, Stone KL, Kodjebacheva G, Yu F, Pedula KL, Ensrud KE, et al. Glaucoma risk and the consumption of fruits and vegetables among older women in the study of osteoporotic fractures. Am J Ophthalmol 2008;145(6):1081-9.