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This research is a quasi-experimental pretest-posttest control group design. The objectives were to compare: 1) the function of patients with bipolar disorder before and after receiving a life goals therapy program, and 2) the function of patients with bipolar disorder receiving life goals therapy program, and the group that received regular caring activities. The 40 samples were patients with bipolar disorder, who sought for received services in outpatients department, Nakornratchasima Rajanagarindra Psychiatric Hospital were recruited to the sample group. They were matched pair by sex and severity of depression or mania, then randomly assigned to the experimental and control groups, 20 subjects in each group. Research instruments comprised of: 1) life goals therapy program, 2) The Functioning Assessment Short Test, 3) Knowledge on Bipolar Disorder Test, 4) Montgomery Asberg Depression Rating Scale, 5) Thai Mania Rating Scale. The content validity of all instruments had verified by 5 professional experts. The 2nd instruments had Cronbach's alpha reliability of 0.87. Descriptive statistics and t-test were used in data analysis. The conclusions of this research were as follows:
1) The level of functioning of patients with bipolar disorder who received a life goals therapy program was significantly lower than that before (p < .05).
2) Patients with bipolar disorder who received a life goals therapy program was significantly lower than those who received the regular caring activities (p < .05).
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