Determination of Erythrocyte Sedimentation Rate (ESR) with a BC-760 Automated Analyzer vs Westergren
Keywords:
Westergren, Automated analyzer BC-760, Erythrocyte sedimentation rate, Leftover specimensAbstract
Purposes: To study the correlation of erythrocyte sedimentation rate measurements between the automated analyzer BC-760 and the standard Westergren method.
Study design: This study was Cross-sectional study.
Materials and Methods: The research conducted was a Cross-sectional Study where the researcher collected leftover specimens, specifically blood samples from patients drawn from venous blood. The samples were placed in K2-EDTA anticoagulant tubes during the period from July 14 to July 21, 2023, totaling 100 cases. The measurement of the erythrocyte sedimentation rate (ESR) was performed using the automatic analyzer BC-760 and the standard Westergren method. The statistical analyses employed included descriptive statistics and Pearson correlation.
Main finding: The majority of the sample group were male (61.00%), with an average age of 61.99 years (SD. = 11.63), and 44.00% were treated in the medical ward. The data analysis revealed a statistically significant correlation between the erythrocyte sedimentation rate measured by the automated analyzer BC-760 and the Westergren method (p < .001), with a correlation coefficient (r) of 0.9469, indicating a strong positive correlation. The Bland-Altman plot analysis showed that most of the data from both methods fell within the limits of agreement (LOA), and no clear pattern was observed, indicating that the measurements from both methods were well correlated.
Conclusions and recommendation : The study demonstrated that the use of the BC-760 automatic analyzer for measuring the erythrocyte sedimentation rate (ESR) is highly effective, showing a very high correlation with the results obtained from the standard Westergren method, which is considered the gold standard. This method can be utilized for patient services, significantly reducing the analysis time from 1 hour to just 90 seconds. It allows for continuous testing and requires a smaller volume of blood, enabling simultaneous analysis with a complete blood count (CBC) using the same tube, thus lowering the costs associated with sample collection.
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