อาการเป็นๆหายๆสัมพันธ์กับระยะเวลาตัดสินใจมารับการรักษา ในผู้ป่วยโรคหลอดเลือดหัวใจเฉียบพลันในพนมเปญ กัมพูชา
คำสำคัญ:
การตอบสนองต่ออาการ, ระยะเวลาตัดสินใจ, โรคหลอดเลือดหัวใจเฉียบพลันบทคัดย่อ
การวิจัยเชิงหาความสัมพันธ์นี้มีวัตถุประสงค์เพื่อศึกษาความสัมพันธ์ระหว่างการตอบสนองต่ออาการกับระยะเวลาตัดสินใจมารับการรักษาในผู้ป่วยโรคหลอดเลือดหัวใจเฉียบพลัน (ACS) ผู้เข้าร่วมวิจัยเป็นผู้ป่วย ACS จำนวน 95 คนที่มารับการรักษาที่แผนกหัวใจในโรงพยาบาลระดับตติยภูมิจำนวน 2 แห่งในพนมเปญ กัมพูชา เก็บข้อมูลด้วยการใช้แบบสัมภาษณ์การตอบสนองต่ออาการ วิเคราะห์ข้อมูลด้วยสถิติเชิงพรรณาและ Gamma Generalized Linear Model ผลการศึกษาพบว่า ผู้เข้าร่วมวิจัยส่วนใหญ่ (63.2%) เป็นเพศชาย ค่ากลางของระยะเวลาการตัดสินใจมารับการรักษา 360 นาที ตัวแปรที่สัมพันธ์กับระยะเวลาตัดสินใจมารับการรักษาคือ การตอบสนองต่ออาการเป็นๆหายๆ และการตอบสนองของผู้พบเห็น ผลการศึกษานี้แสดงให้เห็นว่าผู้ป่วย ACS ในกัมพูชาในระยะเวลาตัดสินใจมารับการรักษานาน ดังนั้นบุคลากรสุขภาพควรเน้นความสำคัญของการให้ข้อมูลเกี่ยวกับลักษณะอาการเพื่อมุ่งลดระยะเวลาตัดสินใจในผู้ที่มีความเสี่ยงสูงในการเกิด ACS
References
1. Amsterdam EA, Wenger NK, Brindis RG, Casey DE, Ganiats TG, Holmes DR, et al. 2014 AHA/ACC Guideline for the management of patients with non–ST elevation acute coronary syndromes. J. Am. Coll. Cardiol. 2014 Dec;64(24):e139 228.
2. Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al.2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST segment elevation. EHJ. 2018 Jan 7;39(2):119–77.
3. Jneid H, Addison D, Bhatt DL, Fonarow GC, Gokak S, Grady KL, et al. 2017 AHA/ACC Clinical performance and quality measures for adults with ST elevation and non–ST-elevation myocardial infarction. J. Am. Coll. Cardiol. 2017 Oct;70(16):2048–90.
4. Ministry of Health of Cambodia. Health report 2018. Phnom Penh, Cambodia: Ministry of Health of Cambodia; 2018.p.89- 103.
5. Calmette Hospital. STEMI Registry 2018. Phnom Penh, Cambodia: Calmette hospital; 2018
6. Joy ER, Kurian J, Gale CP. Comparative effectiveness of primary PCI versus fibrinolytic therapy for ST elevation myocardial infarction: a review of the literature. J. Comp. Eff. Res. 2016 Mar;5(2):217–26.
7. Benamer H, Bataille S, Tafflet M, Jabre P, Dupas F, Laborne FX, et al. Longer pre-hospital delays and higher mortality in women with STEMI: the e-MUST Registry. EuroIntervention. 2016 Aug;12(5):e542–9.
8. Gärtner C, Walz L, Bauernschmitt E, Ladwig K-H. The causes of prehospital delay in myocardial infarction. deutsches aerzteblatt online [Internet]. 2008 Apr 11 [cited 2020 Jan 22]; Available from: https://www.aerzteblatt.de/10.3238/arztebl.2008.0286
9. Margolis G, Letourneau-Shesaf S,Khoury S, Pereg D, Kofman N, Keren G, et al. Trends and predictors of prehospital delay in patients undergoing primary coronary intervention: Coron. Artery Dis. 2018 Aug;29(5):373–7.
10. Natanzon, SS. Segev, A. 2018. Time is myocardium: the focus is ischemic time! IMAJ 2018; 20: 522–523.
11. Noureddine S, Arevian M, Adra M, Puzantian H. Response to signs and symptoms of acute coronary syndrome: differences between Lebanese men and women. Am J Crit Care. 2008 Jan;17(1):26-35.
12. Mackay MH, Ratner PA, Nguyen M, Percy M, Galdas P, Grunau G. Inconsistent measurement of acute coronary syndrome patients’ pre-hospital delay in research: a review of the literature. Eur J Cardiovasc. 2014 Dec;13(6):483–93.
13. Arrebola‐Moreno M, Petrova D, Garrido D, Ramírez‐Hernández JA, Catena A, Garcia‐Retamero R. Psychosocial markers of pre‐hospital decision delay and psychological distress in acute coronary syndrome patients. Br J Health Psychol. 2020 May;25(2):305–23.
14. Guerchicoff A, Brener SJ, Maehara A, Witzenbichler B, Fahy M, Xu K, et al. Impact of delay to reperfusion on reperfusion success, infarct size, and clinical outcomes in patients with ST-segment elevation myocardial Infarction. JACC Cardiovasc. Interv. 2014 Jul;7(7):733–40.
15. Wechkunanukul K, Grantham H, Clark RA. Global review of delay time in seeking medical care for chest pain: An integrative literature review. Aust Crit Care. 2017 Jan;30(1):13–20.
16. Dracup K, Moser DK. Beyond sociodemographics: factors influencing the decision to seek treatment for symptoms of acute myocardial infarction. Heart & Lung. 1997 Jul;26(4):253–62.
17. Fathi M, Rahiminiya A, Zare MA, Tavakoli N. Risk factors of delayed pre-hospital treatment seeking in patients with acute coronary syndrome: a prospective study. Turk. J. Emerg. Med. 2015 Dec;15(4):163–7.
18. Garrido D, Petrova D, Catena A, Ramírez-Hernández JA, Garcia-Retamero R. Recognizing a heart attack: patients’ knowledge of cardiovascular risk factors and its relation to prehospital decision delay in acute coronary syndrome. Front Psychol. 2020 Aug 25;11:2056.
19. Venkatesan VChandiranK, Madhavi S, R. SK, P. K. A study to explore the factors related to treatment seeking delay among adults diagnosed with acute myocardial infarction at KMCH, Coimbatore. Indian Heart J. 2018 Nov;70(6):793–801.
20. Allana S, Khowaja K, Ali TS, Moser DK, Khan AH. Gender differences in factors associated with prehospital delay among acute coronary syndrome patients in Pakistan. J Transcult Nurs. 2015 Nov;26(5):480–90.
21. Petrova D, Garcia-Retamero R, Catena A, Cokely E, Heredia Carrasco A, Arrebola Moreno A, et al. Numeracy predicts risk of pre-hospital decision delay: a retrospective study of acute coronary syndrome survival. Ann Behav Med. 2017 Apr;51(2):292–306.
22. Peng YG, Feng JJ, Guo LF, Li N, Liu WH, Li GJ, et al. Factors associated with prehospital delay in patients with ST-segment elevation acute myocardial infarction in China. Am. J. Emerg. Med. 2014 Apr;32(4):349–55.
23. Youssef GS, Kassem HH, Ameen OA, Al Taaban HS, Rizk HH. Pre-hospital and hospital delay in patients with non-ST elevation acute coronary syndromes in tertiary care. Egypt Heart J. 2017 Sep;69(3):177–81.
24. Tabriz AA, Sohrabi M-R, Yazdani S. Factors associated with delay in thrombolytic therapy in patients with st-elevation myocardial infarction. J Tehran Heart Cent. 2012;7(2):65-71.
25. Yardimci T, Mert H. Turkish. Patients’ decision-making process in seeking treatment for myocardial infarction: patients’ decision-making process. Jpn J Nurs Sci. 2014 Apr;11(2):102–11.
26. Wang X, Hsu LL. Treatment-seeking delays in patients with acute myocardial infarction and use of the emergency medical service. Int. J. Med. Res. 2013 Feb;231-238. doi:10.1177/0300060512474567
27. Mol K., Rahel B., Meeder J., van Casteren BCA., Doevendans P., Cramer MJ. Delays in the treatment of patients with acute coronary syndrome: Focus on pre-hospital delays and non-ST-elevated myocardial infarction. Int. J. Cardiol. 2016;221:1061-1066. doi:10.1016/j.ijcard.2016.07.082
28. Nilsson G, Mooe T, Söderström L, Samuelsson E. Pre-hospital delay in patients with first time myocardial infarction: an observational study in a northern Swedish population. BMC Cardiovasc Disord. 2016;16:93. doi:10.1186/s12872-016-0271-x
29. Sederholm Lawesson S, Isaksson R-M, Ericsson M, Ängerud K, Thylén I. Gender disparities in first medical contact and delay in ST-elevation myocardial infarction: a prospective multicentre Swedish survey study. BMJ Open. 2018 May;8(5):e020211.
2. Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al.2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST segment elevation. EHJ. 2018 Jan 7;39(2):119–77.
3. Jneid H, Addison D, Bhatt DL, Fonarow GC, Gokak S, Grady KL, et al. 2017 AHA/ACC Clinical performance and quality measures for adults with ST elevation and non–ST-elevation myocardial infarction. J. Am. Coll. Cardiol. 2017 Oct;70(16):2048–90.
4. Ministry of Health of Cambodia. Health report 2018. Phnom Penh, Cambodia: Ministry of Health of Cambodia; 2018.p.89- 103.
5. Calmette Hospital. STEMI Registry 2018. Phnom Penh, Cambodia: Calmette hospital; 2018
6. Joy ER, Kurian J, Gale CP. Comparative effectiveness of primary PCI versus fibrinolytic therapy for ST elevation myocardial infarction: a review of the literature. J. Comp. Eff. Res. 2016 Mar;5(2):217–26.
7. Benamer H, Bataille S, Tafflet M, Jabre P, Dupas F, Laborne FX, et al. Longer pre-hospital delays and higher mortality in women with STEMI: the e-MUST Registry. EuroIntervention. 2016 Aug;12(5):e542–9.
8. Gärtner C, Walz L, Bauernschmitt E, Ladwig K-H. The causes of prehospital delay in myocardial infarction. deutsches aerzteblatt online [Internet]. 2008 Apr 11 [cited 2020 Jan 22]; Available from: https://www.aerzteblatt.de/10.3238/arztebl.2008.0286
9. Margolis G, Letourneau-Shesaf S,Khoury S, Pereg D, Kofman N, Keren G, et al. Trends and predictors of prehospital delay in patients undergoing primary coronary intervention: Coron. Artery Dis. 2018 Aug;29(5):373–7.
10. Natanzon, SS. Segev, A. 2018. Time is myocardium: the focus is ischemic time! IMAJ 2018; 20: 522–523.
11. Noureddine S, Arevian M, Adra M, Puzantian H. Response to signs and symptoms of acute coronary syndrome: differences between Lebanese men and women. Am J Crit Care. 2008 Jan;17(1):26-35.
12. Mackay MH, Ratner PA, Nguyen M, Percy M, Galdas P, Grunau G. Inconsistent measurement of acute coronary syndrome patients’ pre-hospital delay in research: a review of the literature. Eur J Cardiovasc. 2014 Dec;13(6):483–93.
13. Arrebola‐Moreno M, Petrova D, Garrido D, Ramírez‐Hernández JA, Catena A, Garcia‐Retamero R. Psychosocial markers of pre‐hospital decision delay and psychological distress in acute coronary syndrome patients. Br J Health Psychol. 2020 May;25(2):305–23.
14. Guerchicoff A, Brener SJ, Maehara A, Witzenbichler B, Fahy M, Xu K, et al. Impact of delay to reperfusion on reperfusion success, infarct size, and clinical outcomes in patients with ST-segment elevation myocardial Infarction. JACC Cardiovasc. Interv. 2014 Jul;7(7):733–40.
15. Wechkunanukul K, Grantham H, Clark RA. Global review of delay time in seeking medical care for chest pain: An integrative literature review. Aust Crit Care. 2017 Jan;30(1):13–20.
16. Dracup K, Moser DK. Beyond sociodemographics: factors influencing the decision to seek treatment for symptoms of acute myocardial infarction. Heart & Lung. 1997 Jul;26(4):253–62.
17. Fathi M, Rahiminiya A, Zare MA, Tavakoli N. Risk factors of delayed pre-hospital treatment seeking in patients with acute coronary syndrome: a prospective study. Turk. J. Emerg. Med. 2015 Dec;15(4):163–7.
18. Garrido D, Petrova D, Catena A, Ramírez-Hernández JA, Garcia-Retamero R. Recognizing a heart attack: patients’ knowledge of cardiovascular risk factors and its relation to prehospital decision delay in acute coronary syndrome. Front Psychol. 2020 Aug 25;11:2056.
19. Venkatesan VChandiranK, Madhavi S, R. SK, P. K. A study to explore the factors related to treatment seeking delay among adults diagnosed with acute myocardial infarction at KMCH, Coimbatore. Indian Heart J. 2018 Nov;70(6):793–801.
20. Allana S, Khowaja K, Ali TS, Moser DK, Khan AH. Gender differences in factors associated with prehospital delay among acute coronary syndrome patients in Pakistan. J Transcult Nurs. 2015 Nov;26(5):480–90.
21. Petrova D, Garcia-Retamero R, Catena A, Cokely E, Heredia Carrasco A, Arrebola Moreno A, et al. Numeracy predicts risk of pre-hospital decision delay: a retrospective study of acute coronary syndrome survival. Ann Behav Med. 2017 Apr;51(2):292–306.
22. Peng YG, Feng JJ, Guo LF, Li N, Liu WH, Li GJ, et al. Factors associated with prehospital delay in patients with ST-segment elevation acute myocardial infarction in China. Am. J. Emerg. Med. 2014 Apr;32(4):349–55.
23. Youssef GS, Kassem HH, Ameen OA, Al Taaban HS, Rizk HH. Pre-hospital and hospital delay in patients with non-ST elevation acute coronary syndromes in tertiary care. Egypt Heart J. 2017 Sep;69(3):177–81.
24. Tabriz AA, Sohrabi M-R, Yazdani S. Factors associated with delay in thrombolytic therapy in patients with st-elevation myocardial infarction. J Tehran Heart Cent. 2012;7(2):65-71.
25. Yardimci T, Mert H. Turkish. Patients’ decision-making process in seeking treatment for myocardial infarction: patients’ decision-making process. Jpn J Nurs Sci. 2014 Apr;11(2):102–11.
26. Wang X, Hsu LL. Treatment-seeking delays in patients with acute myocardial infarction and use of the emergency medical service. Int. J. Med. Res. 2013 Feb;231-238. doi:10.1177/0300060512474567
27. Mol K., Rahel B., Meeder J., van Casteren BCA., Doevendans P., Cramer MJ. Delays in the treatment of patients with acute coronary syndrome: Focus on pre-hospital delays and non-ST-elevated myocardial infarction. Int. J. Cardiol. 2016;221:1061-1066. doi:10.1016/j.ijcard.2016.07.082
28. Nilsson G, Mooe T, Söderström L, Samuelsson E. Pre-hospital delay in patients with first time myocardial infarction: an observational study in a northern Swedish population. BMC Cardiovasc Disord. 2016;16:93. doi:10.1186/s12872-016-0271-x
29. Sederholm Lawesson S, Isaksson R-M, Ericsson M, Ängerud K, Thylén I. Gender disparities in first medical contact and delay in ST-elevation myocardial infarction: a prospective multicentre Swedish survey study. BMJ Open. 2018 May;8(5):e020211.
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2021-12-28
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