Chemotherapy-Induced Peripheral Neuropathy Symptom Experience Perceived by Patients with Colorectal Cancer

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เพชรไพลิน ชัยชาญ
นงลักษณ์ เมธากาญจนศักดิ์

Abstract

This descriptive research aimed to study chemotherapy-induced peripheral neuropathy symptom experience among colorectal cancer patients receiving chemotherapy. The theoretical framework was based on the concept of symptom management proposed by Dodd et al. (2001). The subjects consisted of 206 CRC patients receiving chemotherapy at IPD Unit of Srinagarind Hospital, Faculty of Medicine, Khon Kaen University. The instrument used in this research is a questionnaire consisting of general data questionnaires and questionnaire of chemotherapy-induced peripheral neuropathy symptom experiences. The questionnaires were tested for the CVI was 0.91, 0.87 and 0.89 respectively. The reliability of the instrument was 0.85. The data were collected between March and August 2019, and analyzed through descriptive statistics.


The results are as follows. The most five chemotherapy-induced peripheral neuropathy symptoms of these patients were numbness on the fingers or hand, feel like electric shocked when touch cold or cold objects, numbness on the toes or feet, loss of strength in hands, and tingling fingers or hands. The most five severe symptoms were feel like electric shocked when exposed to cold or cold objects, numbness on the fingers or hand, numbness on the toes or feet, loss of strength in hands, and tingling fingers or hands. The most five suffering symptoms were numbness on the toes or feet, numbness on the fingers or hand,  have writing problem,  constipation and aching or burning pain in fingers or hands. The most five disturbing patient’s daily life were numbness on the fingers or hand,  have writing problem, numbness on the toes or feet, feel like electric shocked when exposed to cold or cold objects, and trouble handling small objects.


              Patients responded to the chemotherapy-induced peripheral neuropathy symptoms by responding to cognitive, physical, psychological and behavioral responses. Most of the patients wanted to find the cause and need help from relatives or medical personnel. Some patient’s don’t need help because they received information that was effects from chemotherapy. The patients response to physical symptoms was most of the patients can do daily activities as usual. They can able to socialize normally, can sleep and can go to work as usual. The patients response to psychological symptoms was most of the patients felt that the symptoms caused them to feel frustrated and feeling that the symptoms cause stress and anxiety, there are only a small number of patient who feel that the symptoms cause bad feelings and feeling lower self-esteem. Most patients responding to behavioral symptoms were having changed their behavior including avoiding cold contact, Exercise of hand and finger, more rest, used massage methods and used warm compress or warm water on hands and feet.


Keyword: chemotherapy-induced peripheral neuropathy

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