Application of classic Chinese medicine formulae in treatment of Coronavirus disease 2019 patients in Malaysia

Abstract

This study aimed to systematically explore the Dr. Bian's herbal formulas in treating COVID-19 effective cases in Malaysia. It further analyzed the prescribed formulations and their characteristics for different syndrome patterns. We treated COVID-19 patients with classic Chinese medicine formulae in Malaysia under the instructions given by Bian Song-jing and achieved therapeutic effects. Our results showed that the disease location of the COVID-19 was mainly in the three Yang channel, especially in Shao Yang channel, the pathogenesis was that the pathogen entered the Shao Yang channel, the pivot’s function was disturbed, or the heat entered deep and formed chest bind, or the pathogen binded in the Yang Ming channel and led to Fu excess patterns. It could also mingle with dampness pathogen, with profuse and turbid phlegm, causing the disease to be prolonged and lingering, which was difficult to heal. If the disease was in the Tai Yang channel, the main symptoms were fever, sore throat and cough, belong to Ma Xing Shi Gan Tang pattern. If the high fever persisted, it was a combination of the three Yang disease, there would be exuberant heat, which belonged to Bai Hu Tang pattern. Chai Hu Xian Xiong Tang was the most frequent prescribed formula, followed by Ma Xing Shi Gan Tang. Chai Hu was the most used herbs, followed by Shi Gao. This article attempts to discuss typical medical records, syndrome differentiation and treatment of COVID-19 based on six-meridians syndrome differentiation and classic Chinese Medicine formulae, intending to offer a valuable reference for clinical practice.