Relationship between Obstructive Sleep Apnea and Extraction Teeth in Orthodontic Treatment

Main Article Content

Wanchaloem Theprungsirikul
Pipop Sutthiprapaporn

Abstract

Obstructive sleep apnea is a common upper airway disorder that, if left untreated, could occur complications including physical, mental, and psychosocial problems. Dentists should be knowledgeable with obstructive sleep apnea and screen patients for the condition by completing an oral examination and administering a questionnaire that includes Berlin questionnaire, Epworth sleepiness scale, and STOP-Bang questionnaire. Additionally, lateral cephalometric radiographs or cone beam computed tomography were examined. Mandibular micrognathism, a hyperdivergent pattern, midface hypoplasia, a decrease in the thyromental distance, and a low hyoid position are all characteristics that are frequently seen in patient with obstructive sleep apnea. Currently, the role of obstructive sleep apnea in orthodontic treatment is more recognized. Both orthodontic treatment combined with tooth extraction and orthodontic treatment combined with mandibular setback surgery require an appropriate treatment. The tooth extraction and mandibular setback will decrease the tongue’s surface area. The tongue is positioned more backward. As a result, the upper airway becomes smaller due to an increase in the contact distance between the soft palate and the tongue. This may lead to the development of obstructive sleep apnea. However, it is unclear from previous studies that orthodontic treatment combined with tooth extraction and orthodontic treatment combined with mandibular setback surgery directly contributes to obstructive sleep apnea. Most of the previous studies may focused on changes in the upper airway spaces without sleep test, a gold standard diagnostic test for diagnosing and describing the severity of obstructive sleep apnea. Therefore, this article presents an overview for orthodontists to realize the importance of obstructive sleep apnea and develop appropriate treatment plans.


 

Article Details

How to Cite
1.
Theprungsirikul W, Sutthiprapaporn P. Relationship between Obstructive Sleep Apnea and Extraction Teeth in Orthodontic Treatment. Thai J Orthod [Internet]. 2024 Apr. 16 [cited 2024 May 6];14(1):41-67. Available from: https://he01.tci-thaijo.org/index.php/THAIORTHO/article/view/259878
Section
Review article

References

Jaimchariyatam N. Obesity and breathing disorder. Chula Med J 2007;51(7):349–65

Pack AI. Advances in sleep-disordered breathing. Am J Respir Crit Care Med 2006;173(1):7–15.

Sateia MJ. International classification of sleep disorders-third edition. Chest 2014;146(5):1387–94.

Flemons WW. Obstructive sleep apnea. N Engl J Med 2002;347(7):498–504.

Sanders MH, Givelber RJ. Overview of obstructive sleep apnea in adults. In: Lee-Chiong T, editor. Sleep: a comprehensive handbook. Hoboken, NJ: John Wiley & Sons; 2005.p.231–40.

Ferguson KA, Ono T, Lowe AA, Ryan CF, Fleetham JA. The relationship between obesity and craniofacial structure in obstructive sleep apnea. Chest 1995;108(2):375–81.

Sutherland K, Lee RWW, Cistulli PA. Obesity and craniofacial structure as risk factors for obstructive sleep apnea: impact of ethnicity: OSA anatomic risk factors and ethnicity. Respirology 2012;17(2):213–22.

Lam B. Craniofacial profile in Asian and white subjects with obstructive sleep apnea. Thorax 2005;60(6):504–10.

Banabilh SM. Orthodontic view in the diagnoses of obstructive sleep apnea. J Orthod Sci 2017;6(3):81-5.

Lowe AA, Santamaria JD, Fleetham JA, Price C. Facial morphology and obstructive sleep apnea. Am J Orthod Dentofacial Orthop 1986;90(6):484–91.

Kim SJ, Ahn HW, Hwang KJ, Kim SW. Respiratory and sleep characteristics based on frequency distribution of craniofacial skeletal patterns in Korean adult patients with obstructive sleep apnea. PLoS One 2020;15(7):e0236284.

Liua Y, Lowea AA, Zengb X, Fub M, Fleethamc JA. Cephalometric comparisons between Chinese and Caucasian patients with obstructive sleep apnea. Am J Orthod Dentofacial Orthop 2000;117(4):479–85.

Kushida CA. A Predictive morphometric model for the obstructive sleep apnea syndrome. Ann Intern Med 1997;127:581.

Banabilh SM, Samsudin AR, Suzina AH, Dinsuhaimi S. Facial profile shape, malocclusion and palatal morphology in Malay obstructive sleep apnea patients. Angle Orthod 2010;80(1):37–42.

Banabilh SM, Suzina AH, Dinsuhaimi S, Singh GD. Cranial base and airway morphology in adult Malays with obstructive sleep apnea. Aust Orthod J 2007;23(2):89-95.

Sheldon SH, Ferber R, Kryger MH, Gozal D, editors. Principles and practice of pediatric sleep medicine. 2nd ed. Philadelphia: W.B. Saunders; 2014.p.175–8.

Mezzanotte WS, Tangel DJ, White DP. Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism). J Clin Invest 1992;89(5):1571–9.

Germec-Cakan D, Taner T, Akan S. Uvulo-glossopharyngeal dimensions in non-extraction, extraction with minimum anchorage, and extraction with maximum anchorage. Eur J Orthod 2011;33(5):515–20.

Chen Y, Hong L, Wang CL, Zhang SJ, Cao C, Wei F, et al. Effect of large incisor retraction on upper airway morphology in adult bimaxillary protrusion patients: three-dimensional multislice computed tomography registration evaluation. Angle Orthod 2012;82(6):964–70.

Wang Q, Jia P, Anderson NK, Wang L, Lin J. Changes of pharyngeal airway size and hyoid bone position following orthodontic treatment of Class I bimaxillary protrusion. Angle Orthod 2012;82(1):115–21.

Bhatia S, Jayan B, Chopra SS. Effect of retraction of anterior teeth on pharyngeal airway and hyoid bone position in Class I bimaxillary dentoalveolar protrusion. Med J Armed Forces India 2016;72:S17–23.

Valiathan M, El H, Hans MG, Palomo MJ. Effects of extraction versus non-extraction treatment on oropharyngeal airway volume. Angle Orthod 2010;80(6):1068-74.

Al Maaitah E, El Said N, Abu Alhaija ES. First premolar extraction effects on upper airway dimension in bimaxillary proclination patients. Angle Orthod 2012;82(5):853–9.

Stefanovic N, El H, Chenin DL, Glisic B, Palomo JM. Three-dimensional pharyngeal airway changes in orthodontic patients treated with and without extractions. Orthod Craniofac Res 2013;16(2):87–96.

Pliska BT, Tam IT, Lowe AA, Madson AM, Almeida FR. Effect of orthodontic treatment on the upper airway volume in adults. Am J Orthod Dentofacial Orthop 2016;150(6):937–44.

Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, et al. Estimation of the global prevalence and burden of obstructive sleep apnea: a literature-based analysis. Lancet Respir Med 2019;7(8):687–98.

Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, Lee A, et al. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med 2017;377(1):13–27.

Romero-Corral A, Caples SM, Lopez-Jimenez F, Somers VK. Interactions between obesity and obstructive sleep apnea. Chest 2010;137(3):711–9.

Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013;177(9):1006–14.

Schwartz AR, Patil SP, Laffan AM, Polotsky V, Schneider H, Smith PL. Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approaches. Proc Am Thorac Soc 2008;5(2):185–92.

Kim Ji, In K, Kim Je, You S, Kang K, Shim J, et al. Prevalence of sleep-disordered breathing in middle-aged Korean men and women. Am J Respir Crit Care Med 2004;170(10):1108-13.

Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Rein J, Vela-Bueno A, et al. Prevalence of sleep-disordered breathing in women: effects of Gender. Am J Respir Crit Care Med 200;163(3):608–13.

Sutherland K, Lee RWW, Cistulli PA. Obesity and craniofacial structure as risk factors for obstructive sleep apnea: impact of ethnicity: OSA anatomic risk factors and ethnicity. Respirology 2012;17(2):213–22.

Fietze I, Laharnar N, Obst A, Ewert R, Felix SB, Garcia C, et al. Prevalence and association analysis of obstructive sleep apnea with gender and age differences - results of SHIP-trend. J Sleep Res 2019;28(5):e12770.

Ip MS, Lam B, Lauder IJ, Tsang KW, Chung KF, Mok YW, et al. A community study of sleep-disordered breathing in middle-aged Chinese men in Hong Kong. Chest 2001;119(1):62-9.

Li MX, Wang Y, Hua SC, Li CM, Wang MP, Liu Y, et al. The prevalence of obstructive sleep apnea-hypopnea syndrome in adults aged over 20 years in Changchun city. Chin J Tuberc Respir Dis 2005;28(12):833–5.

Reddy EV, Kadhiravan T, Mishra HK, Sreenivas V, Handa KK, Sinha S, et al. Prevalence and risk factors of obstructive sleep apnea among middle-aged urban Indians: a community-based study. Sleep Med 2009;10(8):913–8.

Ip MSM, Lam B, Tang LCH, Lauder IJ, Ip TY, Lam WK. A community study of sleep-disordered breathing in middle-aged Chinese women in Hong Kong. Chest 2004;125(1):127–34.

Nakayama-Ashida Y, Takegami M, Chin K, Sumi K, Nakamura T, Takahashi K, et al. Sleep-disordered breathing in the usual lifestyle setting as detected with home monitoring in a population of working men in Japan. Sleep 2008;31(3):419–25.

Neruntarat C, Chantapant S. Prevalence of sleep apnea in HRH Princess Maha Chakri Srinthorn medical center, Thailand. Sleep Breath 2011;15(4):641–8.

Kim SJ, Ahn HW, Hwang KJ, Kim SW. Respiratory and sleep characteristics based on frequency distribution of craniofacial skeletal patterns in Korean adult patients with obstructive sleep apnea. PLoS One 2020;15(7):e0236284.

Durán J, Esnaola S, Rubio R, Iztueta A. Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr. Am J Respir Crit Care Med 2001;163(3 Pt 1):685-9.

Marshall NS, Wong KK, Liu PY, Cullen SR, Knuiman MW, Grunstein RR. Sleep apnea as an independent risk factor for all-cause mortality: the Busselton health study. Sleep 2008;31(8):1079-85.

Hrubos-Strøm H, Randby A, Namtvedt SK, Kristiansen HA, Einvik G, Benth J, et al. A Norwegian population-based study on the risk and prevalence of obstructive sleep apnea. The Akershus sleep apnea project (ASAP). J Sleep Res 2011;20:162–70.

Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013;177(9):1006-14.

Fogel RB, Malhotra A, White DP. Sleep. 2: pathophysiology of obstructive sleep apnoea/hypopnoea syndrome. Thorax 2004;59(2):159-63.

Schwab RJ, Pasirstein M, Pierson R, Mackley A, Hachadoorian R, Arens R, et al. Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging. Am J Respir Crit Care Med 2003;168(5):522-30.

Dempsey JA, Veasey SC, Morgan BJ, O’Donnell CP. Pathophysiology of sleep apnea. Physiol Rev 2010;90(1):47–112.

Spence DL, Han T, McGuire J, Couture D. Obstructive sleep apnea and the adult perioperative patient. J Perianesth Nurs 2015;30(6):528–45.

Eckert DJ, Malhotra A. Pathophysiology of adult obstructive sleep apnea. Proc Am Thorac Soc 2008;5(2):144–53.

Gaspar LS, Álvaro AR, Moita J, Cavadas C. Obstructive sleep apnea and hallmarks of aging. Trends Mol Med 2017;23(8):675–92.

Myers KA, Mrkobrada M, Simel DL. Does this patient have obstructive sleep apnea?: the rational clinical examination systematic review. JAMA 2013;310(7):731-41.

Oztura I, Kaynak D, Kaynak HC. Nocturia in sleep-disordered breathing. Sleep Med 2006;7(4):362–7.

Rodriguez CL, Jaimchariyatam N, Budur K. Rapid eye movement sleep behavior disorder. Chest 2017;152(3):650–62.

Bixler EO, Vgontzas AN, Lin HM, Calhoun SL, Vela-Bueno A, Kales A. Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression. J Clin Endocrinol Metab 2005;90(8):4510-5.

Kapur VK, Baldwin CM, Resnick HE, Gottlieb DJ, Nieto FJ. Sleepiness in patients with moderate to severe sleep-disordered breathing. Sleep 2005;28(4):472-7.

Gottlieb DJ, Whitney CW, Bonekat WH, Iber C, James GD, Lebowitz M, et al. Relation of sleepiness to respiratory disturbance index: the sleep heart health study. Am J Respir Crit Care Med 1999;159(2):502-7.

Kristiansen HA, Kværner KJ, Akre H, Øverland B, Russell MB. Tension-type headache and sleep apnea in the general population. J Headache Pain 2011;12(1):63–9.

Katz I, Stradling J, Slutsky AS, Zamel N, Hoffstein V. Do patients with obstructive sleep apnea have thick necks? Am Rev Respir Dis 1990;141:1228-31.

Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, Patil SP, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 2009;5(3):263-76.

Kohler M, Bloch KE, Stradling JR. The role of the nose in the pathogenesis of obstructive sleep apnea. Curr Opin Otolaryngol Head Neck Surg 2009;17(1):33–7.

Zonato AI, Bittencourt LR, Martinho FL, Júnior JF, Gregório LC, Tufik S. Association of systematic head and neck physical examination with severity of obstructive sleep apnea-hypopnea syndrome. Laryngoscope 2003;113(6):973-80.

Jose N, Shetty S, Mogra S, Shetty VS, Rangarajan S, Mary L. Evaluation of hyoid bone position and its correlation with pharyngeal airway space in different types of skeletal malocclusion. Contemp Clin Dent 2014;5(2):187.

Kushida CA. A predictive morphometric model for the obstructive sleep apnea syndrome. Ann Intern Med 1997;127:581.

Friedman M, Tanyeri H, La Rosa M, Landsberg R, Vaidyanathan K, Pieri S, et al. Clinical predictors of obstructive sleep apnea. Laryngoscope 1999;109(12):1901–7.

Friedman M, Ibrahim H, Joseph NJ. Staging of obstructive sleep apnea/hypopnea syndrome: a guide to appropriate treatment. Laryngoscope 2004;114(3):454–9.

Brodsky L. Modern assessment of tonsils and adenoids. Pediatr Clin North Am 1989;36(6):1551–69.

Ozbek MM, Memikoglu TU, Gögen H, Lowe AA, Baspinar E. Oropharyngeal airway dimensions and functional-orthopedic treatment in skeletal Class II cases. Angle Orthod 1998;68(4):327-36.

Kaur S, Rai S, Sinha A, Ranjan V, Mishra D, Panjwani S. A lateral cephalogram study for evaluation of pharyngeal airway space and its relation to neck circumference and body mass index to determine predictors of obstructive sleep apnea. J Indian Acad Oral Med Radiol 2015;27(1):2.

Battagel J. A cephalometric comparison of subjects with snoring and obstructive sleep apnea. Eur J Orthod 2000;22(4):353–65.

Guttal K, Burde K. Cephalometric evaluation of upper airway in healthy adult population: a preliminary study. J Oral Maxillofac Radiol 2013;1(2):55.

Neelapu BC, Kharbanda OP, Sardana HK, Balachandran R, Sardana V, Kapoor P, et al. Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: a systematic review and meta-analysis of cephalometric studies. Sleep Med Rev 2017;31:79–90.

Netzer NC, Stoohs RA, Netzer CM, Clark K, Strohl KP. Using the Berlin questionnaire to identify patients at risk for the sleep apnea syndrome. Ann Intern Med 1999;131(7):485.

Suksakorn S, Rattanaumpawan P, Banhiran W, Cherakul N, Chotinaiwattarakul W. Reliability and validity of a Thai version of the Berlin questionnaire in patients with sleep disordered breathing. J Med Assoc Thai 2014;97:S46-56.

Chiu HY, Chen PY, Chuang LP, Chen NH, Tu YK, Hsieh YJ, et al. Diagnostic accuracy of the Berlin questionnaire, STOP-BANG, STOP, and Epworth sleepiness scale in detecting obstructive sleep apnea: a bivariate meta-analysis. Sleep Med Rev 2017;36:57–70.

Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 1991;14(6):540–5.

Banhiran W, Assanasen P, Nopmaneejumruslers C, Metheetrairut C. Epworth sleepiness scale in obstructive sleep disordered breathing: the reliability and validity of the Thai version. Sleep Breath 2011;15(3):571–7.

Chung F, Yegneswaran B, Liao P, Chung SA, Vairavanathan S, Islam S, et al. STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesiology 2008;108(5):812–21.

Banhiran W, Durongphan A, Saleesing C, Chongkolwatana C. Diagnostic properties of the STOP-BANG and its modified version in screening for obstructive sleep apnea in Thai patients. J Med Assoc Thai 2014;97(6):644-54.

Kushida CA, Littner MR, Morgenthaler T, Alessi CA, Bailey D, Coleman J Jr, et al. Practice parameters for the indications for polysomnography and related procedures: an update for 2005. Sleep 2005;28(4):499-521.

Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American academy of sleep medicine clinical practice guideline. J Clin Sleep Med 2017;13(3):479-504.

Tuomilehto H, Seppä J, Uusitupa M, Peltonen M, Martikainen T, Sahlman J, et al. The impact of weight reduction in the prevention of the progression of obstructive sleep apnea: an explanatory analysis of a 5-year observational follow-up trial. Sleep Med 2014;15(3):329–35.

Tuomilehto HPI, Seppä JM, Partinen MM, Peltonen M, Gylling H, Tuomilehto JOI, et al. Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea. Am J Respir Crit Care Med 2009;179(4):320–7.

Teerapraipruk B, Chirakalwasan N, Simon R, Hirunwiwatkul P, Jaimchariyatam N, Desudchit T, et al. Clinical and polysomnographic data of positional sleep apnea and its predictors. Sleep Breath 2012;16(4):1167–72.

Patil SP, Winocur E, Buenaver L, Smith MT. Principles and practice of sleep medicine. 6th ed. Philadelphia: Elsevier; 2017.p.1138-53.

Kolla BP, Foroughi M, Saeidifard F, Chakravorty S, Wang Z, Mansukhani MP. The impact of alcohol on breathing parameters during sleep: a systematic review and meta-analysis. Sleep Med Rev 2018;42:59–67.

Pepperell JC, Ramdassingh-Dow S, Crosthwaite N, Mullins R, Jenkinson C, Stradling JR, et al. Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnea: a randomized parallel trial. Lancet 2002;359(9302):204–10.

Jenkinson C, Davies RJ, Mullins R, Stradling JR. Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnea: a randomized prospective parallel trial. Lancet 1999;353(9170):2100–5.

Sullivan CE, Issa FG, Berthon-Jones M, Eves L. Reversal of obstructive sleep apnea by continuous positive airway pressure applied through the nares. Lancet 1981;1(8225):862-5.

Kushida CA, Littner MR, Hirshkowitz M, Morgenthaler TI, Alessi CA, Bailey D, et al. Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders. Sleep 2006;29(3):375–80.

Morgenthaler TI, Aurora RN, Brown T, Zak R, Alessi C, Boehlecke B, et al. Practice parameters for the use of autotitrating continuous positive airway pressure devices for titrating pressures and treating adult patients with obstructive sleep apnea syndrome: an update for 2007. an American academy of sleep medicine report. Sleep 2008;31(1):141–7.

Kushida CA, Morgenthaler TI, Littner MR, Alessi CA, Bailey D, Coleman J, et al. Practice parameters for the treatment of snoring and obstructive sleep apnea with oral appliances: an update for 2005. Sleep 2006;29(2):240–3.

Lettieri CJ, Almeida FR, Cistulli PA, Carra MC. Principles and practice of sleep medicine. Philadelphia: Elsevier; 2017.p.1445-57.

Chan ASL, Sutherland K, Schwab RJ, Zeng B, Petocz P, Lee RWW, et al. The effect of mandibular advancement on upper airway structure in obstructive sleep apnea. Thorax 2010;65(8):726–32.

Lazard DS, Blumen M, Lévy P, Chauvin P, Fragny D, Buchet I, et al. The tongue-retaining device: efficacy and side effects in obstructive sleep apnea syndrome. J Clin Sleep Med 2009;5(5):431–8.

Higurashi N, Kikuchi M, Miyazaki S, Itasaka Y. Effectiveness of a tongue-retaining device. Psychiatry Clin Neurosci 2002;56(3):331–2.

Prinsell JR. Primary and secondary telegnathic maxillomandibular advancement, with or without adjunctive procedures, for obstructive sleep apnea in adults: a literature review and treatment recommendations. J Oral Maxillofac Surg 2012;70(7):1659-77.

Aurora RN, Casey KR, Kristo D, Auerbach S, Bista SR, Chowdhuri S, et al. Practice parameters for the surgical modifications of the upper airway for obstructive sleep apnea in adults. Sleep 2010;33(10):1408-13.

Powell NB. Contemporary surgery for obstructive sleep apnea syndrome. Clin Exp Otorhinolaryngol 2009;2(3):107-14.

Katyal V, Pamula Y, Martin AJ, Daynes CN, Kennedy JD, Sampson WJ. Craniofacial and upper airway morphology in pediatric sleep-disordered breathing: systematic review and meta-analysis. Am J Orthod Dentofacial Orthop 2013;143(1):20-30.

Banhiran W, Wanichakorntrakul P, Metheetrairut C, Chiewvit P, Planuphap W. Lateral cephalometric analysis and the risks of moderate to severe obstructive sleep-disordered breathing in Thai patients. Sleep Breath 2013;17(4):1249–55.

Li KK, Powell NB, Kushida C, Riley RW, Adornato B, Guilleminault C. A comparison of Asian and white patients with obstructive sleep apnea syndrome. Laryngoscope 1999;109(12):1937–40.

Lee RW, Vasudavan S, Hui DS, Prvan T, Petocz P, Darendeliler MA, et al. Differences in craniofacial structures and obesity in Caucasian and Chinese patients with obstructive sleep apnea. Sleep 2010;33(8):1075-80.

Larsen AJ, Rindal DB, Hatch JP, Kane S, Asche SE, Carvalho C, et al. Evidence supports no relationship between obstructive sleep apnea and premolar extraction: an electronic health records review. J Clin Sleep Med 2015;11(12):1443–8.

Riley RW, Powell NB, Guilleminault C, Ware W. Obstructive sleep apnea syndrome following surgery for mandibular prognathism. J Oral Maxillofac Surg 1987;45(5):450-2.

Riley RW, Powell NB. Maxillofacial surgery and obstructive sleep apnea syndrome. Otolaryngol Clin North Am 1990;23(4):809-26.

McNamara JA Jr. A method of cephalometric evaluation. Am J Orthod 1984;86(6):449-69.

Samman N, Tang S, Xia JJ. Cephalometric study of the upper airway in surgically corrected Class III skeletal deformity. Int J Adult Orthodon Orthognath Surg 2002;173:180–90.

Saitoh K. Long-term changes in pharyngeal airway morphology after mandibular setback surgery. Am J Orthod Dentofacial Orthop 2004;125(5):556–61.

Chen F, Terada K, Hua Y, Saito I. Effects of bimaxillary surgery and mandibular setback surgery on pharyngeal airway measurements in patients with Class III skeletal deformities. Am J Orthod Dentofacial Orthop 2007;131(3):372–7.

Eggensperger N, Smolka W, Iizuka T. Long-term changes of hyoid bone position and pharyngeal airway size following mandibular setback by sagittal split ramus osteotomy. J Craniomaxillofac Surg 2005;33(2):111–7.

Degerliyurt K, Ueki K, Hashiba Y, Marukawa K, Nakagawa K, Yamamoto E. A comparative CT evaluation of pharyngeal airway changes in Class III patients receiving bimaxillary surgery or mandibular setback surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105(4):495–502.

Kawamata A, Fujishita M, Ariji Y, Ariji E. Three-dimensional computed tomographic evaluation of morphologic airway changes after mandibular setback osteotomy for prognathism. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89(3):278–87.

Balk EM, Moorthy D, Obadan NO, Patel K, Ip S, Chung M, et al. Diagnosis and treatment of obstructive sleep apnea in adults. Rockville, MD: Tufts evidence-based practice center; 2011. Contract No. 290-2007-10055-1. Sponsored by agency for healthcare research and quality.

Valiathan M, El H, Hans MG, Palomo MJ. Effects of extraction versus non-extraction treatment on oropharyngeal airway volume. Angle Orthod 2010;80(6):1068–74.

Stefanovic N, El H, Chenin DL, Glisic B, Palomo JM. Three-dimensional pharyngeal airway changes in orthodontic patients treated with and without extractions. Orthod Craniofac Res 2013;16(2):87–96.

Wang Q, Jia P, Anderson NK, Wang L, Lin J. Changes of pharyngeal airway size and hyoid bone position following orthodontic treatment of Class I bimaxillary protrusion. Angle Orthod 2012;82(1):115–21.

Gandedkar NH, Chng CK, Por YC, Yeow VKL, Ow ATC, Seah TE. Influence of bimaxillary surgery on pharyngeal airway in Class III deformities and effect on sleep apnea: a STOP-BANG questionnaire and cone-beam computed tomography study. J Oral Maxillofac Surg 2017;75(11):2411–21.