Mechanotransduction Pathways in Periodontal Ligament Cells

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Sutiwa Benjakul
Suwanna Jitpukdeebodintra
Chidchanok Leethanakul


Mechanotransduction has a critical role in the regulation of several physiological processes. Nowadays, many studies investigated these mechanisms. In the field of dentistry, mechanotransduction in periodontal ligament cells plays an important role for periodontal homeostasis and tissue remodeling. In the present review, we consider the major mechanoreceptors, mechanotransduction pathways and mechanotransduction pathways in periodontal ligament cells in response to several mechanical stimuli. To provide more information about these mechanisms in order to properly apply the mechanical stimuli to improve the dental treatment, and also to provide the basic knowledge for further studies.


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Benjakul, S., Jitpukdeebodintra, S., & Leethanakul, C. (2020). Mechanotransduction Pathways in Periodontal Ligament Cells. Thai Journal of Orthodontics วารสารทันตกรรมจัดฟันไทย, 7(1), 29–38. Retrieved from
Review article