Epidemiology of Cleft Lip and Cleft Palate in Thailand

Abstract

The objective of the review entitled “Epidemiology of cleft lip and cleft palate in Thailand” is to collect the results of epidemiological studies of cleft lip and cleft palate in Thailand by reviewing the publications in Thai journals from 1958 to the present. The results showed that the incidence of cleft lip and cleft palate in Thailand was 1.01 - 2.68:1,000 birth children. The incidence classified by cleft lip, cleft palate and combination of cleft lip and palate were 0.16 - 0.90, 0.07 - 0.95 and 0.25 - 0.90 per 1,000 birth children, respectively. The incidence rates are similar between boys and girls. The factors related to cleft lip and cleft palate are sex, socio-economic status, mother’s age during pregnancy, history of such condition among relatives, order of birth, gestational age, month of birth, abnormality during pregnancy, child birth weight, congenital comorbidity, and mother receiving cigarette smoke during pregnancy.