Nutritional Status in Breast Cancer and Colorectal Cancer Patients before Undergoing Chemotherapy

Authors

  • Jinny Techonimit Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University
  • Nutthada Areepium Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University
  • Tippawan Siritientong Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University
  • Bussaba Trakarnsanga Pharmacy Department, King Chulalongkorn Memorial Hospital

Keywords:

nutritional status, breast cancer, colorectal cancer, chemotherapy

Abstract

Currently, cancers are the leading cause of morbidity and mortality worldwide; this is also true for Thailand, especially breast and colorectal cancers. One of the essential problems for cancer patients is malnutrition, which has negative impacts on treatment outcomes and impairs quality of life. Furthermore, among cancer patients treated with chemotherapy, malnutrition may increase the risk of chemotherapy-induced toxicities and result in chemotherapy dose reductions and delays, which can compromise long-term clinical outcomes. This cross-sectional study aimed to assess the nutritional status of breast-cancer and colorectal-cancer patients before undergoing chemotherapy and identify the factors associated with malnutrition. Nutritional status was assessed using the Subjective Global Assessment (SGA) among 50 breast-cancer and 46 colorectal-cancer patients, for whom the first cycle of chemotherapy was scheduled in January- September 2017 at the Outpatient Chemotherapy Center, King Chulalongkorn Memorial Hospital, Bangkok. The prevalence of malnutrition was found to be significantly higher among colorectalcancer patients than breast-cancer patients, at 34.8% and 6.0%, respectively (P<0.001). The study also showed that older age, metastatic cancer, the presence of comorbidity and anemia, were associated with malnutrition. The study findings can help plan appropriate nutritional care for cancer patients before chemotherapy.

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Published

2018-03-30

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Original Articles