Effect of Listening to Intraoperative Hemispheric Synchronized Sounds on Postoperative Cognitive Function after Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial

Effects of Hemispheric Sounds on Postoperative Cognition after CABG

Authors

  • Wirat Wasinwong Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Pongsanae Duangpakdee Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Jutarat Tanasansuttiporn Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Mantana Saetang Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Natparin Saengprateep Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Raphiphat Hirannarong Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.

DOI:

https://doi.org/10.31584/psumj.2026285568

Keywords:

cognitive, cardiac surgery, hemispheric synchronized sounds, pain

Abstract

Objective: This study aimed to evaluate the effect of listening to hemispheric synchronized sounds during surgery on postoperative cognitive function, delirium, and pain scores in patients undergoing coronary artery bypass graft (CABG) surgery.
Material and Methods: This prospective, randomized study was conducted in Songklanagarind Hospital; from February 2021 to December 2022. A total of 70 patients having undergone CABG surgery, were divided into two groups: the “music” group (37 patients) and the control group (33 patients). In the operating room, all patients wore headphones connected to an MP3 player; hemispherical synchronization sounds were played in the music group, beginning immediately after sedation and continuing until the end of surgery. No sounds were played in the control group. Preoperative and postoperative Mini-Mental State Examination (MMSE), Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) 7, and Verbal Numerical Rating Scale pain scores were evaluated in all patients in the first 24 hr after extubation.
Results: Preoperative MMSE scores (26 [interquartile range, IQR: 24,28] vs. 27 [IQR: 23,29], p-value=0.78), postoperative MMSE scores (27 [IQR: 23,29] vs. 27 [IQR: 24,29], p-value=0.42), and CAM-ICU 7 scores (0 [0,1] vs. 0 [0,1], p-value=0.69) did not differ between the control and music groups. However, the maximum pain score (7.6 [1.2] vs. 5 [1.3], p-value<0.001) and postoperative opioid consumption (61.1 [11.8] vs. 31.9 [11.3], p-value<0.001) were higher in the control group than in the music group.
Conclusion: Listening to hemispheric synchronized sounds during an operation did not affect postoperative cognitive dysfunction and delirium. However, music therapy decreased the level of pain and the need for analgesic drug intake postoperatively.

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Published

2026-08-21

How to Cite

1.
Wasinwong W, Duangpakdee P, Tanasansuttiporn J, Saetang M, Saengprateep N, Hirannarong R. Effect of Listening to Intraoperative Hemispheric Synchronized Sounds on Postoperative Cognitive Function after Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial: Effects of Hemispheric Sounds on Postoperative Cognition after CABG . PSU Med J [internet]. 2026 Aug. 21 [cited 2026 Aug. 23];6(2):69-76. available from: https://he01.tci-thaijo.org/index.php/PSUMJ/article/view/285568

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