Development of a Micro Computed Tomography Scanner for Localization of Lesions and Assessment of the Margin Width of Resected Breast Specimens in the Operating Room

Micro-computed Tomography for Breast Biosy Specimen

Authors

  • Puttisak Puttawibul Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
  • Somrit Mahathanobon Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Piyanoot Woodtichartpreecha Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Suphawat Laohawiriyakamol Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Pairash Thajchayapong National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Kriskrai Sitthiseripratip National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Saowapak Thongvigitmanee National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Pasu Sirisalee National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Walita Narkbuakaew National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Sorapong Aootaphao National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Chalinee Thanasubsombat National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Kongyot Wangkaoom National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Atthasak Kiang-ia National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Thossapon Chunkiri National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Danu Prommin National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.
  • Parinya Junhunee National Science and Technology Development Agency (NSTDA), Thailand Science Park, Khlong Luang, Pathum Thani 12120, Thailand.

DOI:

https://doi.org/10.31584/psumj.2022247034

Keywords:

Abnormal calcification, specimen radiography, CT scan of breast tissue specimen

Abstract

Objective: The objective of this study was to develop a micro-computed tomography (micro-CT) scanner machine and software dedicated to the localization of calcification in resected breast tissue specimens in a 3-dimensional image. The micro-CT scanner was designed to be used as a mobile machine, particularly for use in the operating room.
Material and Methods: The system was designed to perform a 360-degree scan on a rotating table between the x-ray source and the detector sensor using a cone beam x-ray. The prototype was developed collaboratively between Prince of Songkla University (PSU) and the National Science and Technology Development Agency, Thailand (NSTDA). This was the first prototype for scanning specimens. The overall scan time and the image reconstruction was 5-10 minutes. The machine was tested for safety by PTEC (Electrical and Electronic Product Testing Center of NSTDA).
Results: The specification of MiniiScan® and preliminary results of 3D image reconstruction of the resected breast tissue specimen by using the MiniiScan® are present in this report. The study evaluated specimens form 31 patients obtained from June 2016 through January 2018. The average scan time was 10.4 minutes. The turnaround time of the conventional technique was 27.9 minutes. The quality of the 3D images as evaluated by PSU staffs was superior to the conventional x-ray images done with the standard mammogram. The 3D images can display the correct position of calcification and a width between calcification to margins in all directional plane.
Conclusion: The 3D images of the prototype intraoperative MiniiScan® scan were superior in quality to the standard mammogram, and had a quicker turnaround time for intraoperative application. Surgeons can use this machine in the operating room instead of relying on the conventional x-rays with a mammogram machine outside the operating theater.

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Published

2022-01-26 — Updated on 2022-02-02

How to Cite

1.
Puttawibul P, Mahathanobon S, Woodtichartpreecha P, Laohawiriyakamol S, Thajchayapong P, Sitthiseripratip K, Thongvigitmanee S, Sirisalee P, Narkbuakaew W, Aootaphao S, Thanasubsombat C, Wangkaoom K, Kiang-ia A, Chunkiri T, Prommin D, Junhunee P. Development of a Micro Computed Tomography Scanner for Localization of Lesions and Assessment of the Margin Width of Resected Breast Specimens in the Operating Room: Micro-computed Tomography for Breast Biosy Specimen. PSU Med J [Internet]. 2022 Feb. 2 [cited 2022 Oct. 7];2(1):9-14. Available from: https://he01.tci-thaijo.org/index.php/PSUMJ/article/view/247034

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