The Study of Cooking Recipes to Reduce Advanced Glycation End Products by Adding Antioxidants Herbs in Fried Pork Cuisine

Authors

  • Sompong Chaiopanont Office of Senior Advisory Committee, Department of Health, Ministry of Public Health
  • Supatta Srithongtae Office of Senior Advisory Committee, Department of Health, Ministry of Public Health
  • Napaphas Thambamroong Office of Senior Advisory Committee, Department of Health, Ministry of Public Health
  • Surachest Chaiprapathong Independent Scholar

Keywords:

cooking process, advanced glycation end products, antioxidants, antiglycation

Abstract

Objective: To study the cooking recipes with antiglycation compounds in order to reduce advanced glycation end products (AGEs). Methods: This experimental study had been trailed a group of recipes by mixing antiglycation-antioxidant herbal vegetables, whether each selected mixing recipe could reduce AGEs in the group of fried pork recipes. The study was conducted in experimental research by analyzing AGEs from protein extract from the well-cooked samples during May-June 2023 via enzyme-linked immunosorbent assay (ELISA) equipment at Laboratory section in Bamras-naradura Institute. Results: The study found that AGEs in the samples: fried pieced pork (Fpp) found 114.45 ± 6.56 µg/ml, Fpp+Garlic 103.51 ± 10.50 µg/ml, Fpp+Curcumin 109.69 ± 7.80 µg/ml, Fpp+Krachai 109.65 ± 4.35 µg/ml, Fpp+Sesame seeds 108.65 ± 9.10 µg/ml, Fpp+lemonade squeeze 104.57 ± 9.45 µg/ml. The item of Fpp+Garlic showed a significance (p=0.032) in reducing AGEs. Fried minced pork (Fmp) found 105.25 ± 6.35 µg/ml, Fmp+Garlic 101.59 ± 8.27 μg/ml, Fmp+Curcumin 99.30 ± 6.46 µg/ml,  Fmp+Krachai 96.93 ± 11.79 µg/ml,  Fmp+Sesame seeds 105.83 ± 5.48µg/ml,  Fmp+ Lemonade squeeze 111.10 ± 3.41 µg/ml, the item of Fmp was found less AGEs than Fpp with significance (p=0.037). Conclusion: This study found that Garlic extra-added in fried pieced pork could help reducing AGEs with statistical significance, also fried minced pork found less amount of AGEs than fried pieced pork.

References

Schmidt AM, Hori O, Brett J, Yan DS, Wautier LJ, Stern D. Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions. Arterioscler Thromb. 1994;14(10):1521-8.

Goldberg T, Cai W, Peppa M, Dardaine V, Baliga BS, Uribarri J, et al. Advanced glycoxidation end products in commonly consumed foods. J Am Diet Assoc 2004;104:1287–91.

Brown MJ. What are Advanced Glycation End Products (AGEs)? Health line; Nutrition [Internet]. 2019 [Cited 2023 Jan 2]. Available from: https://www.healthline.com/nutrition/advanced-glycation-end-products#what-they-are

Rice-Evans CA, Miller N J, Bolwell PG, Bramley PM, Pridham JB. The relative antioxidant activities of plant-derived polyphenolic flavonoids. Free Radic Res 1995;22(4):375-83.

Cahlíková L, Macáková K, Benešová N, Chlebek J, Hošťálková A, Opletal L. Natural compounds (small molecules) as potential and real drugs of Alzheimer's Disease. Studies in Natural Products Chemistry 2014;42:153-94.

Kim CS, Park SV, Kim J. The role of glycation in the pathogenesis of aging and its prevention through herbal products and physical exercise. J Exerc Nutrition Biochem 2017;21(3):55–61.

Broman KW. Experimental design and sample size determination [Internet]. 2024 [Cited 2024 Mar 12]. Available from: https://www.biostat.wisc.edu/~kbroman/talks/acuc_ho.pdf

OECD. Guidance document on good In Vitro method practices (GIVIMP), OECD Series on Testing and Assessment, No. 286. Paris: OECD Publishing; 2018.

Charan J, Kanthira ND. How to calculate sample size in animal studies? J Pharmacol Pharmacother 2013;4(4):303-6.

Ahmad MS, Ahmed N. Antiglycation properties of aged garlic extract: possible role in prevention of diabetic complications. J Nutr 2006;136(3 Suppl):796S-9S.

Galiniak S, Biesiadecki M, Czubat B, Bartusik-Aebisher D. Anti-glycation activity of curcumin. Advances in Hygiene and Experimental Medicine (online) 2019;73:182-8.

ชมนาด สิงหหันต์, ไมตรี สุทธจิตน์. การยับยั้งออกซิเดชันและไกลเคชั่นในโรคเบาหวานโดยผักพื้นบ้านไทย. วารสารมหาวิทยาลัยนเรศวร วิทยาศาสตร์และเทคโนโลยี 2560;25(3):1-11.

Yeh WJ, Hsia SM, Lee WH, Wu CH. Polyphenols with antiglycation activity and mechanisms of action: a review of recent findings. J Food Drug Anal 2017;25(1): 84-92.

Ramful D, Tarnus E, Rondeau P, Da Silva CR , Bahorun T, Bourdon E. Citrus fruit extracts reduce Advanced Glycation End Products (AGEs)- and H2O2-Induced oxidative stress in human adipocytes. J Agric Food Chem 2010;58(20):1119-29.

กระทรวงพาณิชย์. ข้อมูลราคาสินค้าเกษตร กระเทียม งาดำ [อินเทอร์เน็ต]. 2567 [เข้าถึงเมื่อ 30 มี.ค.2567]. เข้าถึงได้จาก:https://data.moc.go.th/OpenData/GISProductPrice?product_id=W18078&from_date=2024-02-25&to_date=2024-03-30&task=search

กรมส่งเสริมการเกษตร. ราคาขาย กระชายดำ (บาท/กิโลกรัม) [อินเทอร์เน็ต]. 2562 [เข้าถึงเมื่อ 30 มี.ค.2567]. เข้าถึงได้จาก: http://www.agriman.doae.go.th/home/news/2563/53-54.pdf

ตลาดไท. ราคาสินค้า ขมิ้นเหลือง [อินเทอร์เน็ต]. 2567 [เข้าถึงเมื่อ 30 มี.ค.2567]. เข้าถึงได้จาก: https://talaadthai.com/products/turmeric-9723-2529

สำนักงานเศรษฐกิจการเกษตร. มะนาว ราคารับซื้อรายวันสินค้าเกษตรกรรมที่ตลาดกลางและตลาดสำคัญ ศูนย์สารสนเทศการเกษตร สำนักงานเศรษฐกิจการเกษตร ข้อมูลเดือน ธ.ค.2566 [อินเทอร์เน็ต]. 2567 [เข้าถึงเมื่อ30 มี.ค.2567]. เข้าถึงได้จาก: https://www.oae.go.th/view/

Abcam. AGE (Advanced Glycation End) Assay Kit (ab238539) [Internet]. 2023 [Cited 2023 Jul 28]. Available from: https://www.abcam.com/products/assay-kits/age-advanced-glycation-end-assay-kit-ab238539.html

Serdar CC, Cihan M, Yücel D, Serdar MA. Sample size, power and effect size revisited: simplified and practical approaches in pre-clinical, clinical and laboratory studies. Biochem Med (Zagreb) 2021;31(1):010502.

ปรัญรัชต์ ธนวิยุทธ์ภักดี. ไกลเคชั่นกับการเกิดโรคในมนุษย์. วารสารพิษวิทยาไทย 2559;31(2):84-96.

Uribarri J, Woodruff S, Goodman S, Cai W, Chen X, Pyzik R, et al. Advanced glycation end products in foods and a practical guide to their reduction in the diet. J Am Diet Assoc 2010;110(6):911-16.

Piya Pangsapa. Michelin Guide วิธีทำรากผักชี กระเทียม พริกไทย สูตรไม่ลับแห่งสามเกลอคู่ครัวไทย. [อินเทอร์เน็ต]. 2567 [เข้าถึงเมื่อ 31 มี.ค.2567]. เข้าถึงได้จาก: https://guide.michelin.com/th/th/article/dining-in/recipe-how-to-make-raak-pakchi-kratiem-prik-thai-the-three-buddies-of-thai-cuisine

Sawabe A, Yamashita A, Fujimatsu M, Takeda R. Development of Evaluation Methods for Anti-Glycation Activity and Functional Ingredients Contained in Coriander and Fennel Seeds. Processes 2022;10:982.

Kazeem MI, Akanji MA, Hafizur Rahman M, Choudhary MI. Antiglycation, antioxidant and toxicological potential of polyphenol extracts of alligator pepper, ginger and nutmeg from Nigeria. Asian Pac J Trop Biomed 2012;2(9):727-32.

Shakthi Deve A, Sathish kumar T, Kumaresan K, Raphea VS. Extraction process optimization of polyphenols from Indian Citrus sinensis – as novel antiglycative agents in the management of diabetes mellitus. J Diabetes Metab Disord 2014;13(1):11.

Chiang Chan EW, Eng SY, Tan YP, Wong ZC, Lye PY, Tan LN. Antioxidant and Sensory Properties of Thai Herbal Teas with Emphasis on Thunbergia laurifolia Lindl. Chiang Mai J Sci 2012;39(4):599-609.

Downloads

Published

2024-04-19

How to Cite

1.
Chaiopanont S, Srithongtae S, Thambamroong N, Chaiprapathong S. The Study of Cooking Recipes to Reduce Advanced Glycation End Products by Adding Antioxidants Herbs in Fried Pork Cuisine. JPMAT [Internet]. 2024 Apr. 19 [cited 2024 May 4];14(1):130-4. Available from: https://he01.tci-thaijo.org/index.php/JPMAT/article/view/269721

Issue

Section

Original Article