Biological Risk Factors of each Type of Developmental Delay among Children in Lampang Hospital

Authors

  • Pakawadi Vuttipittayamongkol Department of Pediatrics, Lampang Hospital
  • Kawinratt Srisutheenon Department of Pediatrics, Lampang Hospital
  • Prakasit Wannapaschaiyong Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

children with developmental delays, biological risk factors, maternal illness, children’s illness

Abstract

Objective: To identify risk factors affecting developmental delays in early childhood in Lampang Province to develop monitoring processes and promote age-appropriate development for children at risk of developmental delays. Methods: This retrospective case-control study collected data from the medical patient files of children with developmental delays whom developmental and behavioral pediatricians diagnosed and typically developing children born at the same time as children with developmental delays in Lampang Hospital, from 2 months to 5 years of age, from 1 January 2020 to 31 December 2021. Biological risk factors affecting developmental delay were identified by using multivariate risk difference regression analysis. Results: A total of 447 children were recruited for this study, divided into 149 children with developmental delays and 298 with typical development. Among children with delayed development, 57% have delayed language development. After risk difference regression analysis, the biological risk factors that were significantly associated with delayed development included males, history of birth asphyxia, microcephaly, more than five hospitalization days in the neonatal intensive care unit, hearing loss, malnutrition, twin pregnancy, maternal anemia, and maternal chorioamnionitis. Conclusion: Biological risk factors that affect developmental delays in children include maternal illness and malnutrition during pregnancy, perinatal complications, and children’s illness and nutritional status. Certain risk factors can be monitored and prevented to reduce developmental delays in early childhood. In addition, recognizing the risk factors for developmental delays can lead healthcare providers and parents to closely monitor developmental problems and promote the development of children with these risk factors from birth.

References

Choo YY, Agarwal P, How CH, Yeleswarapu SP. Developmental delay: identification and management at primary care level. Singapore Med J 2019;60(3):119-23.

World Health Organization. Developmental difficulties in early childhood: prevention, early identification, assessment, and intervention in low and middle-income countries: a review [Internet]. 2012 [cited 2024 Mar 4]. Available from: https://apps.who.int/iris/handle/10665/97942

Salinpramote B. Quality of life among caregivers of children with developmental delay. Research and Developmental Health System Journal 2023;15(3):114-27.

บำเพ็ญ พงศ์เพชรดิถ, บุษบา อรรถาวีร์. ปัจจัยที่ส่งผลต่อการพัฒนาการเด็กปฐมวัยไทย : ศูนย์อนามัยที่ 5. วารสารเกื้อการุณย์ 2563;27(1):59-70.

Drozd-Da bronska M, Trusewicz R, Ganczak M. Selected risk factors of developmental delay in polish infants: a case-control study. Int J Environ Res public health 2018;15(12):2715.

Khandelwal N, Mandliya J, Nigam K, Patil V, Mathur A, Pathak A. Determinants of motor, language, cognitive, and global developmental delay in children with complicated severe acute malnutrition at the time of discharge: an observational study from central India. PLoS One 2020;15(6):e0233949.

ภควดี วุฒิพิทยามงคล. ผลการประเมินพัฒนาการเด็กกลุ่มเสี่ยงในช่วงปฐมวัยในโครงการบูรณาการพัฒนาการเด็กล้านนาที่โรงพยาบาลลำปาง. ลำปางเวชสาร 2561;39(1):18-32.

Strasburger VC, Jordan AB, Donnerstein E. Children, adolescents, and the media: health effects. Pediatr Clin North Am 2012;59(3):533-87.

Simms MD. Language development and communication disorders. In: Kliegman RM, Stanton BF, St Geme lll JW, Schor NF, Behrman RE, editors. Nelson textbook of pediatrics. 21st ed. Philadelphia: Elsevier; 2019. p.273-83.

Adani S, Cepanec M. Sex differences in early communication development: behavioral and neurobiological indicators of more vulnerable communication system development in boys. Croat Med J 2019;60(2):141-49.

Tal G, Cohen A, Habib S, Tirosh E. Decreased head circumference velocity as related to developmental deficit in infancy. Pediatric Neurol 2012;47(5):341-4.

Aggarwal A, Mittal H, Patil R, Debnath S, Rai A. Clinical profile of children with developmental delay and microcephaly. J Neurosci Rural Pract 2013;4(3):288-91.

Thorpe K. Twin children’s language development. Early Hum Dev 2006;82(6):387-95.

Singh A, Kamble B, Gangwar K, Roy N. A review of developmental delay and its determinants in under five children. National Journal of Medical and Allied Sciences 2017;6(2):66-70.

Saleem J, Zakar R, Bukhari GMJ, Fischer F. Developmental delay and its predictors among children under five years of age with uncomplicated severe acute malnutrition: a cross-sectional study in rural Pakistan. BMC Public Health 2021;21:1397.

Ohal MM, John M. A prospective study of the hearing loss in global developmental delay children. International Journal of Scientific Study 2019;6(11):146-54.

Sharma N, Masood J, Singh SN, Ahmad N, Mishra P, Singh S, et al. Assessment of risk factors for developmental delays among children in a rural community of North India: a cross-sectional study. J Educ Health Promot 2019;8:112.

Schmeltz LR. Principles and guidelines for early hearing detection and intervention programs. JEHDI 2019;4(2):1-44.

McGowan EC, Hofheimer JA, O’Shea TM, Kilbride H, Carter BS, Check J, et al. Analysis of neonatal neurobehavior and developmental outcomes among preterm infants. JAMA Netw Open 2022;5(7):e2222249.

Bajalan Z, Alimoradi Z. Risk factors of developmental delay among infants aged 6-18 months. Early Child Development and Care 2018;190(11):1691-99.

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Published

2024-04-11

How to Cite

1.
Vuttipittayamongkol P, Srisutheenon K, Wannapaschaiyong P. Biological Risk Factors of each Type of Developmental Delay among Children in Lampang Hospital. JPMAT [Internet]. 2024 Apr. 11 [cited 2024 Dec. 26];14(1):76-91. Available from: https://he01.tci-thaijo.org/index.php/JPMAT/article/view/268799

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Original Article