Childhood diabetes mellitus in Phra Nakhon Si Ayutthaya Hospital

Authors

  • Manassaya Sitthisan Department of Pediatrics, Phra Nakhon Si Ayutthaya Hospital

Keywords:

DM, diabetes mellitus, childhood diabetes mellitus, type 1 diabetes mellitus, type 2 diabetes mellitus

Abstract

Diabetes mellitus (DM) is a chronic disease that impacts the quality of life in any age, but there are no data of the attributes of childhood DM in Phra Nakhon Si Ayutthaya Hospital. Therefore, the purpose of this retrospective study was to describe the prevalence, type of DM, clinical presentation, laboratory data, treatment regimen, and complications, as well as to compare the attributes of Type 1 DM (T1DM) and Type 2 DM (T2DM). The sample comprised 34 children with diabetes, and the data were collected between October 1, 2015 to September 30, 2020, in the Outpatient Department. The results showed that the prevalence of childhood DM were 9.1 per 10,000 patients. There were 17 patients (50%) with T1DM, 15 patients (44%) with T2DM, and two patients (6%) with other types. Classical clinical DM was found in almost all of the T1DM patients, but the T2DM patients required blood screening or a urine test to conduct the diagnosis. A lower HbA1C level was found in the conventional insulin regimen group than the basal bolus regimen group in T1DM. In conclusion, the prevalence of childhood DM was slightly low. As such, a blood test would be required for the diagnosis of T2DM, especially in cases with obesity. Conventional insulin regimen had a lower HbA1c; thus, further research would be needed to determine the risk factors of poor glycemic control in patients undertaking the basal bolus regimen in T1DM.       

References

Trepatchayakorn S, Supornsilchai V, Wacharasindhu S, Aroonparkmongkol S, Sahakitrungruang T. Trends and characteristics of childhood diabetes in a tertiary care center in Thailand. Asian Biomedicine 2014;8:707-15.

Nantarakchaikul P. Children with diabetes mellitus in Suratthani Hospital. Region 11 Medical Journal 2018;29:353-64.

Patterson CC, Dahlquist GG, Gyürüs E, Green A, Soltész G. Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet (London, England) 2009;373(9680):2027-33.

Smith TL, Drum ML, Lipton RB. Incidence of childhood type I and non-type 1 diabetes mellitus in a diverse population: the Chicago Childhood Diabetes Registry, 1994 to 2003. Journal of pediatric endocrinology & metabolism : JPEM 2007;20:1093-107.

กมลทิพย์ วิจิตรสุนทรกุล, สัญชัย ชาสมบัติ. การศึกษาสถานการณ์การเสียชีวิตก่อนวัยอันควรของประเทศไทย [อินเทอร์เน็ต]. 2560 [เข้าถึงเมื่อ 5 ธ.ค.2563]. เข้าถึงได้จาก:http://www.thaincd.com/document/file/info/non-communicable.

Centers for Disease Control and Prevention. Diabetes death rates among youths aged≤19 Years-United States, 1968–2009. Morbidity and Mortality Weekly Report 2012;61:869-72.

สมาคมโรคเบาหวานแห่งประเทศไทย. แนวทางเวชปฏิบัติสำหรับโรคเบาหวาน 2560. ปทุมธานี: สมาคมโรคเบาหวานแห่งประเทศไทย; 2560.

Likitmaskul S, Wacharasindhu S, Rawdaree P, Ngarmukos C, Deerochanawong C, Suwanwalaikorn S, et al. Thailand diabetes registry project: type of diabetes, glycemic control and prevalence of microvascular complications in children and adolescents with diabetes. J Med Assoc Thai. 2006;89 Suppl 1:S10-6.

Jaruratanasirikul S, Thammaratchuchai S, Sriplung H. Trends of childhood diabetes in Southern Thailand: 20-year experience in a tertiary medical center. World J Pediatr 2017;13:566-70.

World Health Organization. BMI for age (5-19 years) [Internet]. 2007 [cited 2020 Dec 17]. Available from: https://www.who.int/tools/growth-reference-data-for-5to19-years/indicators/bmi-for-age.

ชมรมโภชนาการเด็กแห่งประเทศไทย ราชวิทยาลัยกุมารแพทย์แห่งประเทศไทย. แนวทางเวชปฏิบัติการป้องกันและรักษาโรคอ้วนในเด็ก พ.ศ. 2557 [อินเทอร์เน็ต]. 2557 [เข้าถึงเมื่อ 17 ธ.ค. 2563]. เข้าถึงได้จาก: http://www.thaipediatrics.org/Media/media-20161208151655.pdf.

อังคนีย์ ชะนะกุล, ธวัชชัย ดีขจรเดช. ความดันโลหิตสูงในเด็ก. จุฬาลงกรณ์เวชสาร 2553;10:54:487- 502.

Panamonta O, Laopaiboon M, Tuchinda C. Incidence of childhood type 1 (insulin dependent) diabetes mellitus in northeastern Thailand. J Med Assoc Thai 2000;83:821-4.

Haliloğlu B, Abalı S, Buğrul F, Çelik E, Baş S, Atay Z, et al. The Distribution of different types of diabetes in childhood: A Single center experience. J clin Res Pediatr Endocrinol 2018;10:125-30.

Demir F, Günöz H, Saka N, Darendeliler F, Bundak R, Baş F, et al. Epidemiologic features of type 1 diabetic patients between 0 and 18 years of age in İstanbul city. J Clin Res Pediatr Endocrinol 2015;7:49-56.

Lowe WL, Scholtens DM, Kuang A, Linder B, Lawrence JM, Lebenthal Y, et al. Hyperglycemia and adverse pregnancy outcome follow-up study (HAPO FUS): Maternal gestational diabetes mellitus and childhood glucose metabolism. Diabetes Care 2019;42:372-80.

Downloads

Published

2021-05-13

How to Cite

1.
Sitthisan M. Childhood diabetes mellitus in Phra Nakhon Si Ayutthaya Hospital. JPMAT [Internet]. 2021 May 13 [cited 2024 Nov. 8];11(1):50-66. Available from: https://he01.tci-thaijo.org/index.php/JPMAT/article/view/244658

Issue

Section

Original Article